ArticleFrontiers in aging neuroscience2025
Relationship between Body Roundness Index and cognitive impairment in middle-aged and older adults: a population-based cross-sectional study.
Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Impact of body roundness index on cognitive decline and cognitive impairment in middle-aged and older adults ≥ 45 years: mediating role of biological aging.Scientific reports · 2026Article
- Spatial heterogeneity and influencing factors of cognitive impairment among elderly hypertensive patients: evidence from rural communities in China.BMC geriatrics · 2026Article
- Association of central adiposity indices with cognitive impairment in elderly populations: Development and validation of a risk prediction nomogram using NHANES and CHARLS cohorts.Journal of Alzheimer's disease : JAD · 2026Article
- Mediation by atherogenic index of plasma of the association between body roundness index and cognitive impairment in older Chinese people: an analysis using health check-up data.Frontiers in public health · 2026Article
- Novel Anthropometric Indices and Probability of Adequate Nutrient Intake in the Older Polish Population.Nutrients · 2025Article
- Associations of the body roundness index with cognitive function in US older adults and the mediating role of depression: a cross-sectional study from the NHANES 2011-2014.Scientific reports · 2025Article
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12 authors.
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Abstract
Background: Cognitive impairment is a growing public health concern, particularly in aging populations. Obesity, as measured by various indices, has been linked to cognitive decline, but the relationship between Body Roundness Index (BRI) and cognitive impairment remains unclear. This study aims to evaluate the association between BRI and cognitive impairment in a rural, low-income, low-education population in China and to determine if BRI can be used as an independent predictor of cognitive decline. Methods: This cross-sectional study included the participants aged 35-95 years from rural Tianjin, China. The mean age of the study population was 64.35 ± 7.58 years. Data were collected through face-to-face interviews, physical examinations, and laboratory tests. Cognitive function was assessed using the Mini-Mental State Examination (MMSE), and BRI was calculated and grouped into quartiles. Univariate and multivariate logistic regression analyses were performed to examine the relationship between BRI and cognitive impairment. Subgroup analyses were conducted to explore interactions between BRI, age, gender, and hypertension. The dose-response relationship was analyzed using restricted cubic spline models. Results: Of the participants, 36.5% had cognitive impairment. Multivariate analysis showed that women, individuals aged 65 and over, and those with hypertension had a higher risk of cognitive impairment. Participants in the second quartile of BRI had a 31% lower risk of cognitive impairment compared to the first quartile (OR: 0.69, 95% CI: 0.51-0.94, Conclusion: Body Roundness Index, in conjunction with age, gender, and hypertension, can serve as a useful predictor of cognitive impairment, particularly in younger populations. Early identification of individuals at risk through BRI may facilitate timely interventions, reducing the burden of cognitive decline on patients and healthcare systems.
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