Evidence mapPaperPMID 40046795Full record

ArticleInternational journal of health sciences

Antioxidative and ameliorative properties of probiotic-enriched fermented and unfermented turmeric-camel milk in streptozotocin-induced diabetes and oxidative stress in rats.

Yousef M Alharbi, Mohammed Alkhidhr, Hassan Barakat

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Article in International journal of health sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yousef M AlharbiDepartment of Medical Biosciences, College of Veterinary Medicine, Qassim University, Buraydah, Saudi Arabia.
Mohammed AlkhidhrDepartment of Medical Biosciences, College of Veterinary Medicine, Qassim University, Buraydah, Saudi Arabia.
Hassan BarakatDepartment of Food Science and Human Nutrition, College of Agriculture and Food, Qassim University, Buraydah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Probiotic-enriched fermented turmeric-camel milk (FTCM) and unfermented (TCM) were examined on streptozotocin (STZ)-induced type 2 diabetes and oxidative stress in rats. Methods: High phenolics and antioxidant activity were found in TCM and FTCM. FTCM and TCM at 10 or 20 mL/kg were investigated for antidiabetic and hypolipidemic effects in an animal model. The positive group diabetic rats (DR) received 45 mg/kg STZ intraperitoneally; G3 DR (DR+Met) received 50 mg metformin kg Results: TCM and FTCM had strong phenolics and antioxidant potential. High-performance liquid chromatography analysis quantified ten phenolic acids and four flavonoids, with ferulic acid and resveratrol dominating. TCM and FTCM dramatically decreased random blood glucose and fasting blood glucose. The hypolipidemic effects of TCM and FTCM were more significant at 20 mL/kg than at 10 mL/kg, with substantial reductions in triglycerides, total cholesterol, high- and low-density lipoproteins cholesterol, and very-low-density lipoproteins cholesterol. TCM and FTCM at 20 mL/kg improved liver and kidney functions more than metformin or 10 mL/kg. FTCM and TCM dose-dependently increased antioxidant enzyme activity, glutathione, catalase, and superoxide dismutase, and decreased malondialdehyde. Histopathologically, TCM and FTCM showed typical Langerhans cell and acini structure, outperforming metformin. Conclusion: TCM and FTCM may help profitably manage diabetes complications and oxidative stress.

Indexed as

Antidiabetesantioxidantsdiabetes mellitusoxidative stressturmeric-camel milk

Identifiers

PMID40046795
PMCPMC11877055

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.