ArticleJournal of general internal medicine2026
Predictors and Consequences of Poor Health Trajectories Among US Adults Ages 50-64: A Latent Class Growth Analysis.
Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Article
- Analysis of the Spatiotemporal Digestion Characteristics of Pine Pollen Processed by Different Methods in Middle-Aged Adults Using an In Vitro Digestion Model System.Foods (Basel, Switzerland) · 2026Article
- Self-reported health as a predictor of cardiometabolic multimorbidity in Chinese older adults: a national cross-sectional study.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundUS middle-aged adults have experienced concerning declines in health and life expectancy since 2010.
objectiveTo investigate which groups of middle-aged adults are at risk of poor health trajectories, identify predictors of unhealthy aging, and assess potential consequences on health care utilization, costs, and mortality after these adults age into older adulthood.
designWe used longitudinal survey data from the nationally representative, biennial Health and Retirement Study (HRS) to follow a representative sample of adults age 51 and older.
participantsA total of 12,333 US community-dwelling respondents. MAIN MEASURES: We estimated health trajectories from biennial self-reported health status and limitations in activities of daily living and instrumental activities of daily living. Predictors of health trajectories included sociodemographic, clinical, and health care characteristics. Consequences of poor health trajectories after age 65 included self-reported hospitalizations, out-of-pocket medical costs, and mortality. KEY
resultsWe identified four distinct trajectories: "Healthy Agers" (14.2%), "Less Healthy Agers" (40.7%), "Unhealthy Agers, Low Baseline" (31.0%), and "Persistently Ill" (14.1%). Predictors of the "Persistently Ill" and "Unhealthy Agers, Low Baseline" trajectories included male gender, non-Hispanic Black race, and Hispanic ethnicity. Predictors of less healthy and unhealthy aging trajectories included ≤ high school education, income ≤ 250% of federal poverty level, smoking, obesity, and chronic diseases including diabetes, whereas continuous insurance coverage in ages 50-64, compared with intermittent or no insurance, was associated with lower odds of less healthy and unhealthy aging trajectories. After age 65, less healthy and unhealthy aging trajectories were associated with greater hospitalizations, out-of-pocket costs, and mortality compared with "Healthy Agers."
conclusionThe findings suggest that unhealthy aging trajectories may frequently be set prior to age 50. Policy interventions earlier in life, such as availability of consistent health insurance coverage in early and mid-life, may mitigate downstream poor health and health care outcomes in older adulthood.
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