Evidence map›Paper›PMID 40050899›Full record

ArticleInternational journal of mental health systems2025

Barriers and potential solutions for effective integration of depression care into non-communicable diseases clinics in Malawi: a qualitative end-point evaluation of the SHARP randomized controlled trial.

Chifundo Colleta Zimba, Jullita Kenala Malava, MacDonald Mbota, Maureen Matewere, Harriet Akello, Christopher F Akiba, Kelsey R Landrum, Abigail Morrison, Vivian Go, Mina C Hosseinipour and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in International journal of mental health systems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03711786 (The Sub-Saharan Africa Regional Partnership), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03711786 nacompletednot on this map

The Sub-Saharan Africa Regional Partnership (SHARP) for Mental Health Capacity Building

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2019 to 2022Enrolled946ConditionsDepressionArmsBasic implementation package, Enhanced implementation package
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Treatment Experiences of Individuals With Co-Occurring Mental Health and Substance Use Disorders and Perspectives of Mental Health Workers in Ashanti Region, Ghana.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chifundo Colleta ZimbaThe University of North Carolina Project, Lilongwe, Malawi. colleta.zimba@gmail.com.
Jullita Kenala MalavaMalawi Epidemiology and Intervention Research Unit (MEIRU), Lilongwe, Malawi.
MacDonald MbotaThe University of North Carolina Project, Lilongwe, Malawi.
Maureen MatewereThe University of North Carolina Project, Lilongwe, Malawi.
Harriet AkelloThe University of North Carolina Project, Lilongwe, Malawi.
Christopher F AkibaRTI International, Research Triangle Park, NC, USA.
Kelsey R LandrumGillings School of Global Public Health, Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Abigail MorrisonGillings School of Global Public Health, Department of Health Behavior, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Vivian GoGillings School of Global Public Health, Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Mina C HosseinipourThe University of North Carolina Project, Lilongwe, Malawi.
Bradley N GaynesGillings School of Global Public Health, Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Michael UdediMinistry of Health, Lilongwe, Malawi.
Jones MasiyeMinistry of Health, Lilongwe, Malawi.
Brian W PenceGillings School of Global Public Health, Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Funding

Sub-Saharan Africa Regional Partnership (SHARP) for Mental Health Capacity Building - Scale-Up ComponentU19MH113202 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HOSSEINIPOUR, MINA CHRISTINE, PENCE, BRIAN W · 2017 to 2021
$4.1M
National Institute of Heath U19MH113202-04S1NIMH NIH HHS U19 MH113202NIMH NIH HHS U19MH113202-01
6 · The paper itself

Abstract

backgroundThe sub-Saharan African Regional Partnership for mental health and capacity building (SHARP) study was a clinic-randomized trial of two implementation strategies for integrating depression screening and treatment into non-communicable diseases' (NCD) clinics in Malawi between 2019 and 2022. We report on the barriers to implementing depression care integration at SHARP study sites and potential solutions.

methodsN = 39 in-depth interviews with participants from all ten sites were conducted, recorded, transcribed, coded in NVivo 12 and analyzed by qualitative experts. We used thematic analysis to identify implementation challenges and potential solutions. The Consolidated Framework for Implementation Research helped to develop guides and organize the results.

resultsOuter setting barriers included high workload (due to high patient volume, increased paperwork, shortage of staff), the effects of coronavirus disease 2019 (COVID-19) pandemic, staff turnover and negative provider attitudes. Limited clinic space arose as an inner setting barrier. Workload can be overcome by increasing the number of NCD personnel, decentralizing the depression/NCD services and integrating mental health and NCD documents (implementation process). The COVID-19 pandemic presented unique challenges including fear of interpersonal contact and changes in scheduling staff that were difficult to overcome in the short term. To deal with the effects of staff turnover, participants identified the need for continuous depression training to new providers. Lobbying for more rooms from leadership can address concerns of limited space. To reduce negative provider attitudes, participants urged facility leadership to make themselves available for consultations and mentorship and to provide continuous learning opportunities such as refresher trainings.

conclusionThe experience in the SHARP study highlights the need for a culture of continuous learning and adaptation in healthcare settings, enabling the development of strategies to overcome evolving challenges. Planning for the integration of mental health and NCD care should extend beyond immediate challenges and consider long-term goals and sustainability.

trial registrationThis study reports part of the findings from the endpoint evaluation of the SHARP clinical trial that is registered at ClinicalTrials.gov, NCT03711786 first posted 20,181,018.

Indexed as

BarriersCommon mental disordersDepressionDiabetesEvaluationHypertensionImplementation scienceIntegrationNCDsQualitativeTask shifting

Identifiers

PMID40050899
PMCPMC11884183

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.