Evidence map›Paper›PMID 40052673›Full record

ArticleeLife2025

Adult neurogenesis through glial transdifferentiation in a CNS injury paradigm.

Sergio Casas-Tinto, Nuria Garcia-Guillen, María Losada-Perez

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. The Repair Manual of a Fruit Fly Brain.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Regulating glial morphogenesis: insights fromFrontiers in cell and developmental biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sergio Casas-TintoInstituto Cajal (CSIC), Madrid, Spain.ORCID https://orcid.org/0000-0002-9589-9981
Nuria Garcia-GuillenInstituto Cajal (CSIC), Madrid, Spain.
María Losada-PerezInstituto Cajal (CSIC), Madrid, Spain.ORCID https://orcid.org/0000-0002-6717-7762

Funding

Ministerio de Ciencia e Innovación PI22CIII/00062Ministerio de Ciencia e Innovación PID2022-137751OA-I00
6 · The paper itself

Abstract

As the global population ages, the prevalence of neurodegenerative disorders is fast increasing. This neurodegeneration as well as other central nervous system (CNS) injuries cause permanent disabilities. Thus, generation of new neurons is the rosetta stone in contemporary neuroscience. Glial cells support CNS homeostasis through evolutionary conserved mechanisms. Upon damage, glial cells activate an immune and inflammatory response to clear the injury site from debris and proliferate to restore cell number. This glial regenerative response (GRR) is mediated by the neuropil-associated glia (NG) in

Indexed as

Cell TransdifferentiationCentral Nervous SystemNeurogenesisNeurogliaAnimalsAstrocytesDrosophila melanogasterNeuronsCNS injuryD. melanogasterglianeuroscienceregenerationtransdifferentiationventral nerve cord

Identifiers

PMID40052673
PMCPMC11888597

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.