Evidence map›Paper›PMID 40053754›Full record

Trial reportJournal of medical Internet research2025

Web-Based Application for Reducing Methamphetamine Use Among Aboriginal and Torres Strait Islander People: Randomized Waitlist Controlled Trial.

Rachel Reilly, Rebecca McKetin, Federica Barzi, Tayla Degan, Nadine Ezard, Katherine Conigrave, Julia Butt, Yvette Roe, Handan Wand, Brendan Quinn and 4 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rachel ReillyWardliparingga Aboriginal Health Equity, South Australian Health and Medical Research Institute, Adelaide, Australia.ORCID 0000-0003-2107-9187
Rebecca McKetinNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.ORCID 0000-0003-2833-4830
Federica BarziPoche Centre for Indigenous Health, University of Queensland, Brisbane, Australia.ORCID 0000-0001-7427-0167
Tayla DeganNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.ORCID 0000-0002-3552-4627
Nadine EzardNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.ORCID 0000-0002-7495-8305
Katherine ConigraveCentral Clinical School, Sydney Medical School, University of Sydney, Sydney, Australia.ORCID 0000-0002-6428-1441
Julia ButtDiscipline of Psychology and Social Sciences, School of Arts and Humanities, Edith Cowan University, Perth, Australia.ORCID 0000-0003-4714-2252
Yvette RoeMolly Wardaguga Institute for First Nations Birth Rights, Charles Darwin University, Casuarina, Northern Territory, Australia.ORCID 0000-0001-6851-4233
Handan WandThe Kirby Institute, University of New South Wales, Sydney, Australia.ORCID 0000-0002-8279-7652
Brendan QuinnBurnet Institute, Melbourne, Australia.ORCID 0000-0002-2977-3133
Wade LongbottomSouth Coast Aboriginal Medical Service Corporation, Nowra, Australia.ORCID 0009-0005-1197-4980
Carla TreloarCentre for Social Research in Health, University of New South Wales, Sydney, Australia.ORCID 0000-0002-8230-0386
Adrian DunlopSchool of Medicine and Public Health, University of Newcastle, Newcastle, Australia.ORCID 0000-0003-2394-5966
James WardPoche Centre for Indigenous Health, University of Queensland, Brisbane, Australia.ORCID 0000-0002-2892-4542

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDigital interventions can help to overcome barriers to care, including stigma, geographical distance, and a lack of culturally appropriate treatment options. "We Can Do This" is a web-based app that was designed with input from cultural advisors and end users to support Aboriginal and Torres Strait Islander people seeking to stop or reduce their use of methamphetamine and increase psychosocial well-being.

objectiveThis study aimed to evaluate the effectiveness of the "We Can Do This" web-based app as a psychosocial treatment for Aboriginal and Torres Strait Islander people who use methamphetamine.

methodsThe web app was evaluated using a randomized waitlist controlled parallel group trial. Participants were Aboriginal and Torres Strait Islander people aged 16 years or older who self-identified as having used methamphetamine at least weekly for the past 3 months. Participants were randomized on a 1:1 ratio to receive either access to the web-based app for 6 weeks or a waitlist control group. Both groups received access to a website with harm minimization information. The primary outcome was days of methamphetamine use in the past 4 weeks assessed at 1, 2, and 3 months post randomization. Secondary outcomes included severity of methamphetamine dependence (Severity of Dependence Scale [SDS]), psychological distress (Kessler 10 [K10]), help-seeking behavior, and days spent out of role due to methamphetamine use.

resultsParticipants (N=210) were randomized to receive either access to the web-based app (n=115) or the waitlist control condition (n=95). Follow-up was 63% at 1 month, 57% at 2 months, and 54% at 3 months. There were no significant group differences in days of methamphetamine use in the past 4 weeks at 1 the month (mean difference 0.2 days, 95% CI -1.5 to -2), 2 months (mean difference 0.6 days, 95% CI -1 to 2.4 days) or 3 months (mean difference 1.4 days, 95% CI -0.3 to 3.3 days) follow-up. There were no significant group differences in K10 scores, SDS scores, days out of role, or help-seeking at any of the 3 follow-up timepoints. There was poor adherence to the web-based app, only 20% of participants in the intervention group returned to the web-based app after their initial log-in. Participants cited personal issues and forgetting about the web-based app as the most common reasons for nonadherence.

conclusionsWe found poor engagement with this web-based app. The web-based app had no significant effects on methamphetamine use or psychosocial well-being. Poor adherence and low follow-up hindered our ability to accurately evaluate the effectiveness of the web-based app. Future web-based apps for this population need to consider methods to increase participant engagement.

trial registrationAustralian New Zealand Clinical Trials Registry ACTRN12619000134123p; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=376088. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.2196/14084.

Indexed as

Amphetamine-Related DisordersInternet-Based InterventionAdolescentAdultAustraliaAustralian Aboriginal and Torres Strait Islander PeoplesFemaleHumansMaleMethamphetamineMiddle AgedMobile ApplicationsWaiting ListsYoung AdultMethamphetamineAboriginal and Torres Strait Islander Healthappdigital interventionseffectivenessmethamphetaminemethamphetamine usemobile phonepsychosocial distresspsychosocial wellbeingrandomised controlled trialsubstance usetherapeutic programtreatmentweb-based intervention

Identifiers

PMID40053754
PMCPMC11909485

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.