Evidence map›Paper›PMID 40055616›Full record

ArticleBMC infectious diseases2025

Detection of toxoplasma tachyzoites in the cerebrospinal fluid of a COVID-19 positive SLE patient: a case study.

Ling Chen, Xiangping Hou, Hao Fu, Rui Zheng, Yonghong Xiao, Lifeng Xiang, Yunhua Dong

Abstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ling Chen *Department of clinical laboratory, the First People's Hospital of Yunnan Province, Kunming, 650032, China.
Xiangping Hou *Department of clinical laboratory, the First People's Hospital of Yunnan Province, Kunming, 650032, China.
Hao FuDepartment of clinical neurology, the First People's Hospital of Yunnan Province, Kunming, 650032, China.
Rui ZhengDepartment of clinical laboratory, the First People's Hospital of Yunnan Province, Kunming, 650032, China.
Yonghong XiaoDepartment of clinical laboratory, the First People's Hospital of Yunnan Province, Kunming, 650032, China.
Lifeng XiangDepartment of Reproductive Medicine, NHC Key Laboratory of Healthy Birth and Birth Defect Prevention in Western China, the First People's Hospital of Yunnan Province, Kunming, 650032, China. xlflotus@aliyun.com.
Yunhua DongDepartment of Reproductive Medicine, NHC Key Laboratory of Healthy Birth and Birth Defect Prevention in Western China, the First People's Hospital of Yunnan Province, Kunming, 650032, China. doninhua@163.com.

Funding

the Joint Special Funds for the Department of Science and Technology of Yunnan Province‑Kunming Medical University 202101AY070001-260, 202301AY070001-298the Key Projects of Yunnan Province Science and Technology Department 202302AA310044the National Natural Science Foundation of China 82160294, 82360304
6 · The paper itself

Abstract

The recurrence of latent toxoplasmosis is a frequent cause of toxoplasmic encephalopathy in individuals with immunosuppressive conditions or medication. If left untreated or diagnosed is delayed, it often resulting in fatality. The pathogen of Toxoplasma gondii has been identified in cerebrospinal fluid cytology and a limited number of documented cases of cerebral toxoplasmosis, typically observed in those with acquired immunodeficiency syndrome (AIDS). We report the identification of Toxoplasma gondii tachyzoites in the cerebrospinal fluid of a patient diagnosed with systemic lupus erythematosus (SLE) and concurrent SARS-CoV-2 positive infection. The presented case suggests that cerebral toxoplasmosis should be promptly considered when patients with systemic lupus erythematosus exhibit neurological manifestations.

Indexed as

COVID-19Lupus Erythematosus, SystemicToxoplasmaToxoplasmosis, CerebralCerebrospinal FluidHumansSARS-CoV-2AIDSSLEToxoplasmic encephalopathyToxoplasmosis

Identifiers

PMID40055616
PMCPMC11887088

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.