Evidence mapPaperPMID 40055752Full record

GuidelineReproductive biology and endocrinology : RB&E2025

Diagnosis and management of infertility in patients with polycystic ovary syndrome (PCOS): guidelines from the Italian Society of Human Reproduction (SIRU) and the Italian Centers for the Study and Conservation of Eggs and Sperm (CECOS Italy).

Stefano Palomba, Giuseppe Seminara, Francesco Tomei, Angelo Marino, Giuseppe Morgante, Domenico Baldini, Enrico Papaleo, Guglielmo Ragusa, Antonio Aversa, Adolfo Allegra and 3 more

Abstract readPractice Guideline
In one paragraph

Guideline in Reproductive biology and endocrinology : RB&E, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
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  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stefano PalombaDepartment of Medical-Surgical Science and Translational Medicine, Obstetrics & Gynecology, Sapienza University of Rome, Via Di Grottarossa 1039, Rome, Italy. prof.stefano.palomba@gmail.com.
Giuseppe SeminaraDepartment of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Francesco TomeiCenter of Medicine, San Donà di Piave, VE, Italy.
Angelo MarinoANDROS Day Surgery Clinic, Palermo, Italy.
Giuseppe MorganteUnit of Medically Assisted Reproduction and Department of Molecular and Developmental Medicine, Siena University Hospital and University of Siena, Siena, Italy.
Domenico BaldiniMomò Fertilife, Bisceglie, BT, Italy.
Enrico PapaleoObstetrics and Gynecology Department, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Guglielmo RagusaUnit of Reproductive Medicine, Hospital "Borgo Trento", Verona, Italy.
Antonio AversaDepartment of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Adolfo AllegraANDROS Day Surgery Clinic, Palermo, Italy.
Antonino GuglielminoUnit of Reproductive Medicine (U.M.R.), HERA Center, Sant'Agata li Battiati, CT, Italy.
Edgardo SomiglianaInfertility Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and University of Milan, Milan, Italy.
SIRU-CECOS Working Group on Italian Guideline for Infertility in PCOS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The polycystic ovary syndrome (PCOS) is a multifaced disease of the reproductive age associated with several comorbidities including infertility. Very few documents regarding the management of the infertility in women with PCOS, including guidelines, position papers and consensus conferences, are available in the literature. The Italian Law indicates that health professionals must comply with the recommendations set out in the guidelines developed by public and private bodies and institutions, as well as scientific societies and technical-scientific associations of the health professions, except for specific cases. Unfortunately, no guideline for the diagnosis and the management of infertility in women with PCOS is currently available in Italy. In 2024, the Italian Society of Human Reproduction (SIRU) and the Italian Centers for the Study and Conservation of Eggs and Sperm (CECOS Italy) pointed out the need to produce Italian guidelines on this topic and established a specific working group to develop those guidelines. The working group chose to adapt the guideline with highest quality to the Italian context rather than developing a de novo document. The International Evidence-Based Guideline for the Assessment and Management of PCOS guidelines were selected. All recommendations regarding the diagnosis and the management of women with PCOS and infertility extracted, adapted to the Italian context and improved incorporating new recommendations or practical comments and suggestions where needed.

Indexed as

Infertility, FemalePolycystic Ovary SyndromeFemaleHumansItalyReproductive Techniques, AssistedSocieties, MedicalGuidelinesInfertilityManagementPCOSPolycystic ovary syndrome

Identifiers

PMID40055752
PMCPMC11889853

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.