Observational studyJapanese journal of ophthalmology2025
Real-world practice patterns for dry eye diagnosis: a multicenter observational study in Taiwan.
Observational study in Japanese journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients Undergoing Cataract Surgery: A Prospective Double-Masked Randomized Controlled Clinical Trial.Ophthalmology and therapy · 2025Article
- Comparison of Postoperative Outcomes in 71 Patients Undergoing Cataract Surgery at a Single Center with and Without Preoperative Keratostill Moisturizing Eye Drops.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
purposeTo investigate the concordance between Asia Dry Eye Society (ADES) diagnostic criteria and real-world hospital-based practice, and to analyze the clinical characteristics of patients with dry eye disease (DED), in Taiwan. STUDY
designNoninterventional, cross-sectional, retrospective clinical study.
methodsData were analyzed for adults with newly diagnosed DED from three tertiary hospitals. The primary endpoint was the proportion of patients diagnosed with DED who fulfilled ADES criteria for DED. Other outcomes were DED classification and severity, tear breakup time (TBUT), Schirmer's test, corneal fluorescein staining (CFS) severity, 12-item Ocular Surface Disease Index (OSDI) questionnaire scores, and presence of meibomian gland dysfunction (MGD).
resultsA total of 213 patients, mean (SD) age 54.3 (15.0) years, 79.8% female, were evaluated. Mean TBUT of 3.0 (2.6) sec and mean OSDI score of 36.5 (21.0) indicated severe DED at diagnosis. Most patients (87.3%) had a TBUT ≤5 sec, fulfilling ADES diagnostic criteria. Short TBUT (≤5 sec) and OSDI ≥13 had high sensitivity for diagnosing DED (87.3% and 90.1%, respectively), whereas an abnormal Schirmer's test (69.5%) and abnormal CFS (42.3%) were less sensitive. MGD was diagnosed in 56.3% of patients. Dry eye-related characteristics in the non-short TBUT (>5 sec) group diverged for objective but not subjective clinical tests. Most common first treatments were artificial tears (95.8%) and corticosteroids (85.0%).
conclusionsDED diagnosis in routine hospital practice in Taiwan is highly concordant (87.3%) with ADES diagnostic criteria. TBUT appears to be an effective diagnostic tool for identifying dry eye in patients across symptom severity, etiology and age.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.