Evidence map›Paper›PMID 40056364›Full record

ReviewTissue engineering and regenerative medicine2025

Branched Polymer Architecture for Modulating Interactions in Material-Bio Interface.

Fahimeh Taghavimandi, Min Gyu Kim, Mingyu Lee, Kwangsoo Shin

Abstract readReview
In one paragraph

Review in Tissue engineering and regenerative medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. 2D MoSNano convergence · 2026
    Article
  2. Review
  3. Cell-Cell or Cell-Biomaterial Interactions for Therapeutic Application.Tissue engineering and regenerative medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fahimeh TaghavimandiDepartment of Polymer Science and Engineering and Program in Environmental and Polymer Engineering, Inha University, Incheon, 22212, Republic of Korea.
Min Gyu KimDepartment of Polymer Science and Engineering and Program in Environmental and Polymer Engineering, Inha University, Incheon, 22212, Republic of Korea.
Mingyu LeeDepartment of Polymer Science and Engineering and Program in Environmental and Polymer Engineering, Inha University, Incheon, 22212, Republic of Korea.
Kwangsoo ShinDepartment of Polymer Science and Engineering and Program in Environmental and Polymer Engineering, Inha University, Incheon, 22212, Republic of Korea. kwangsoo.shin@inha.ac.kr.ORCID http://orcid.org/0000-0001-5337-0679

Funding

the National Research Foundation of Korea RS-2024-00342075the National Research Foundation of Korea RS-2024-00437611
6 · The paper itself

Abstract

backgroundBranched polymers, including star, dendrimers, comb, and biomimetic polymers, are increasingly recognized for their potential in tissue engineering. Their unique architectures and functional properties contribute to enhanced mechanical strength, bioactivity, and adaptability of scaffolds and hydrogels.

objectiveThis review explores the diverse applications of branched polymers in tissue engineering and regenerative medicine, emphasizing their role in mimicking the extracellular matrix (ECM) and modulating interactions at the material-bio interface. The structural features of branched polymers, including branching density and functional group distribution, are highlighted for their influence on drug delivery, mechanical properties, and cellular interactions.

resultsBranched polymers offer distinct advantages in tissue engineering: Star polymers: Provide tunable elasticity and facilitate long-range mechanical networking. Dendrimers: Enable precise functionalization for targeted drug delivery and cell signaling. Comb polymers: Enhance porosity and nutrient exchange in scaffolds. Biomimetic polymers: Mimic natural biological systems, promoting cellular adhesion, proliferation, and differentiation.

conclusionBranched polymers represent a versatile and promising platform for tissue engineering and regenerative medicine. Their ability to modulate biological interactions and adapt to diverse functional requirements underscores their potential to advance the field.

Indexed as

Biocompatible MaterialsBiomimetic MaterialsPolymersTissue EngineeringAnimalsDendrimersExtracellular MatrixHumansHydrogelsRegenerative MedicineTissue ScaffoldsBiocompatible MaterialsDendrimersHydrogelsPolymersBiomaterialsBranched polymersExtracellular matrix (ECM)Material-bio interfacePolymer architecture

Identifiers

PMID40056364
PMCPMC12122963

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.