Evidence map›Paper›PMID 40058880›Full record

ArticleBritish journal of haematology2025

Real-world insights from a cohort of approximately 2000 individuals who were analysed using a freely available next-generation sequencing anaemia screening programme.

Jorune Balciuniene, Saliha Yilmaz, Satheesh Chonat, Rachael F Grace, Gerald A Soff, Yaddanapudi Ravindranath, Bertil Glader, Paola Bianchi, Bryan McGee, Archana M Agarwal and 1 more

Abstract readLetter
In one paragraph

Article in British journal of haematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jorune BalciunieneRevvity Omics, Clinical Services, Revvity, Inc., Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0000-0001-8063-5302
Saliha YilmazAgios Pharmaceuticals, Inc., Cambridge, Massachusetts, USA.
Satheesh ChonatDepartment of Pediatrics, Emory University School of Medicine, and Aflac Cancer and Blood Disorders Center at Children's Healthcare of Atlanta, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-5909-0800
Rachael F GraceDepartment of Pediatrics, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-7302-0449
Gerald A SoffDepartment of Hematology, Sylvester Comprehensive Cancer Center, University of Miami Health System, Miami, Florida, USA.ORCID https://orcid.org/0000-0002-8781-903X
Yaddanapudi RavindranathDepartment of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, USA.
Bertil GladerPediatric Hematology/Oncology, Stanford University School of Medicine and Lucile Packard Children's Hospital, Palo Alto, California, USA.
Paola BianchiUOC Ematologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0001-5976-5233
Bryan McGeeAgios Pharmaceuticals, Inc., Cambridge, Massachusetts, USA.
Archana M AgarwalDepartment of Pathology, University of Utah/ARUP Laboratories, Salt Lake City, Utah, USA.
Geetha PuthenveetilDepartment of Pediatric Hematology, Children's Hospital of Orange County, Orange, California, USA.ORCID https://orcid.org/0000-0002-3466-9082

Funding

Agios Pharmaceuticals, Inc.
6 · The paper itself

Abstract

Data from a large cohort of individuals referred for NGS testing evaluate the utility of next-generation sequencing in clinical practice for diagnosing hereditary haemolytic anaemias.

Indexed as

Anemia, Hemolytic, CongenitalGenetic TestingHigh-Throughput Nucleotide SequencingAdultCohort StudiesFemaleHumansMaleMiddle Aged

Identifiers

PMID40058880
PMCPMC12166331

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.