ArticleACS omega2025
Genotoxic and Hematological Effects Associated with Chronic Dietary Mercury Toxicity in Juvenile Tilapia
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Protective role of probiotics or Spirulina platensis supplementation against mercury-induced hematological, histopathological, and antioxidant-immune gene dysregulation in Nile Tilapia (Oreochromis niloticus).Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Alkaline Decomposition Kinetics in Ca(OH)Toxics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fish farming and artisanal fishing represent important protein sources for riverside communities and populations of small towns in the Amazon. In recent decades, the Amazon basin has been the target of environmental contamination by mercury (Hg), which warns of possible adverse effects of human exposure through food. In this study, we evaluated the effect of mercury bioaccumulation in juvenile tilapia exposed via dietary intake. The fish were fed commercial feed supplemented with methylmercury chloride for a period of 28 days. Hematological parameters (hemogram, hematocrit (Hct), hemoglobin (Hgb), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC)) and genotoxic effects in blood (micronucleus (MN), erythrocytic nuclear abnormalities (ENAs), DNA damage) were analyzed. Total mercury (THg) was determined in muscle tissue and blood. Hg bioaccumulation increased 7-fold in exposed fish, representing a body accumulation rate of 41%. No variation in growth performance or feeding habits was observed. The following biomarkers Hgb, thrombocytes (Trb), MCH, MCHC, MN and ENAs showed variation as a function of exposure time. Compensatory mechanisms of defense metabolism showed greater deficiency between 21 and 28 days.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.