ReviewJournal of multidisciplinary healthcare2025
Mapping the Knowledge Landscape of and Emerging Future Trends in Stem Cell Therapy for Osteoarthritis: A Bibliometric Analysis of the Literature From 1998 to 2024.
Review in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Mesenchymal stem cells and extracellular vesicles for knee osteoarthritis: clinical application, mechanism exploration and prospect.Stem cell research & therapy · 2025Review
- Unraveling the Scientific Landscape of Osteoarthritis: Dynamics of Publications over Five Decades.Bioengineering (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The purpose of this study was to conduct a bibliometric analysis of the literature on stem cell therapy for osteoarthritis (OA) to visualize recent developments, identify hot spots, and determine trends in the field. Background: OA is a chronic disease that affects the joints and their surrounding tissues, leading to progressive damage to the articular cartilage and ultimately to the subchondral bone and the surrounding synovial structures. OA is a disabling disease with an increasing incidence and prevalence in the general population. Modulation of immunity and inflammation and improvement of cell survival and differentiation through multidirectional differentiation of stem cells is a potential strategy for the treatment of OA. Methods: We searched for publications on "stem cell therapy for osteoarthritis" in the Web of Science (WOS) core collection database from 1998-2024 and summarized the results, including year of publication, country, institution, author, and collaborative network generated using VOSviewer and Citespace. In addition, research trends were identified. Finally, we summarized the hot topics and identified future research trends. Results: This study ultimately included 2341 valid papers, with a trend toward a gradual increase in the number of publications over time. The country, institution, author, and journal with the highest number of publications and citations were China, the University of California system, Sekiya I, and Osteoarthritis and Cartilage, respectively. High-frequency keyword clusters included cell therapy, stem cells, tissue engineering, and extracellular vesicles. Conclusion: Through visualization and analysis, we elucidated the trends and research hotspots in the field over the past five years. The analysis revealed that stem cell transplantation and exosome therapy for OA may be the focus of future research. This study lays the foundation for future research and clinical work on stem cell therapy in this field.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.