Evidence map›Paper›PMID 40061016›Full record

ArticlemicroPublication biology2025

Schwann cell deletion of

Derek Silvius, Edward Hurley, Yannick Poitelon, Kay-Uwe Wagner, M Laura Feltri, Teresa M Gunn

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in microPublication biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Neuronal Deletion ofBiomolecules · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Derek SilviusMcLaughlin Research Institute, Great Falls, Montana, United States.
Edward HurleyDepartments of Neurology and Biochemistry, Institute for Myelin and Glia Exploration, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, United States.
Yannick PoitelonAlbany Medical College, Albany, New York, United States.
Kay-Uwe WagnerDepartment of Oncology and Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, United States.
M Laura FeltriDepartments of Neurology and Biochemistry, Institute for Myelin and Glia Exploration, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, United States.
Teresa M GunnMcLaughlin Research Institute, Great Falls, Montana, United States.

Funding

Modulation of Exosome Release for Functional Restoration in Age-related Retinal DisordersP20GM152335 · NIGMS · MC LAUGHLIN RESEARCH INSTITUTE · PI Renee A Reijo Pera · 2024 to 2026
$11.1M
NIGMS NIH HHS P20 GM152335
6 · The paper itself

Abstract

Myelinating Schwann cells are particularly susceptible to defects in endosomal trafficking. TSG101 is a component of the endosomal trafficking machinery that mediates the sorting of ubiquitinated receptors into multivesicular bodies. We previously demonstrated that deleting

Identifiers

PMID40061016
PMCPMC11889464

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.