Evidence map›Paper›PMID 40061357›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Yun Freudenberg-Hua, Luca Giliberto, Cristina D'Abramo, Wentian Li, Yilong Ma, Alison Goate, Jeremy Koppel

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yun Freudenberg-HuaCenter for Alzheimer's Disease Research, Institute of Molecular Medicine, the Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.
Luca GilibertoCenter for Alzheimer's Disease Research, Institute of Molecular Medicine, the Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.
Cristina D'AbramoCenter for Alzheimer's Disease Research, Institute of Molecular Medicine, the Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.ORCID 0000-0003-4470-4942
Wentian LiDepartment of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY 11794, USA.
Yilong MaCenter for Neurosciences, Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.
Alison GoateRonald M. Loeb Center for Alzheimer's disease, Dept. of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-0576-2472
Jeremy KoppelCenter for Alzheimer's Disease Research, Institute of Molecular Medicine, the Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.

Funding

Identification of Risk Genes SupplementK08AG054727 · NIA · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI FREUDENBERG-HUA, YUN · 2017 to 2022
$739k
NIA NIH HHS K08 AG054727
6 · The paper itself

Abstract

Plasma levels of protein biomarkers glial fibrillary acidic protein (GFAP) and neurofilament light (NEFL) are key dementia biomarkers, but it is unclear how risk genes for Alzheimer's disease (AD) influence levels of these biomarkers. We investigated the association of the established high-effect variants for AD in

Identifiers

PMID40061357
PMCPMC11888501

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.