SynthesisFrontiers in medicine2025
Research status and hotspots of hypothermia and human diseases: a bibliometric analysis.
Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Artificial intelligence in breast ultrasound: a systematic review of research advances.Frontiers in oncology · 2025Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hypothermia has been strongly associated with human diseases; it affects life safety. Therapeutic hypothermia generates good results for certain diseases, without serious complications. In clinical practice, research on the treatment of hypothermia and severe hypothermia-induced diseases have achieved fruitful results. However, no bibliometric analysis has been conducted. In this study, we explored the research status and hotspots of hypothermia and human diseases by conducting a bibliometric analysis. Methods: Articles on hypothermia and human diseases were collected from the Web of Science Core Collection. From 1 January 2005 to 31 August 2024, A total of 1,553 articles were retrieved. After excluding irrelevant articles, 706 articles were analyzed. Results: The United States and China published the maximum number of research articles on hypothermia and human diseases. Among institutes, Johns Hopkins University and Harvard University published the maximum number of research articles. Scholars, including Ishikawa Takaki, Maeda Hitoshi, and Michiue Tomomi, constituted a highly productive group of authors. The journal, Therapeutic Hypothermia and Temperature Management published the highest number of articles, and Nature Reviews Drug Discovery had the highest impact factor. Cluster analysis of all keywords primarily focused on the following research directions: (i) hypothermia-related injury, (ii) hypothermia treatment, and (iii) the mechanism underlying hypothermia. Conclusion: This bibliometric study comprehensively summarizes the impact of hypothermia on human diseases and the research overview of the use of moderate hypothermia for treatment. This paper clarifies the research status, frontiers and hotspots, and also puts forward new insights for hypothermia research: strengthen research cooperation to improve the depth of research, increase support for areas with insufficient medical conditions; in the future, single-cell multiomics technology will be used to explore cell types sensitive to different low temperatures and corresponding molecular mechanisms; non-coding RNA regulation will be used to achieve precision treatment of hypothermia diseases; Organoids will be an important object of hypothermia research. These research insights can provide reference for researchers.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.