Evidence map›Paper›PMID 40063165›Full record

SynthesisLa Radiologia medica2025

Can MRI predict return to sport after anterior cruciate ligament reconstruction? A systematic review of the literature.

Riccardo D'Ambrosi, Luca Maria Sconfienza, Domenico Albano, Amit Meena, Elisabeth Abermann, Christian Fink

Abstract readSystematic Review
In one paragraph

Synthesis in La Radiologia medica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  8. Pediatric ACL Injuries: A Current Concepts Review.Journal of clinical medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Riccardo D'AmbrosiIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Luca Maria SconfienzaIRCCS Istituto Ortopedico Galeazzi, Milan, Italy. io@lucasconfienza.it.ORCID http://orcid.org/0000-0003-0759-8431
Domenico AlbanoIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Amit MeenaDepartment of Orthopaedics, Shalby Hospital, Jaipur, India.
Elisabeth AbermannGelenkpunkt-Sports and Joint Surgery FIFA Medical Centre of Excellence, Innsbruck, Austria.
Christian FinkGelenkpunkt-Sports and Joint Surgery FIFA Medical Centre of Excellence, Innsbruck, Austria.

Funding

Ministero della Salute Ricerca corrente
6 · The paper itself

Abstract

purposeTo analyze whether magnetic resonance imaging (MRI) can predict return to sport after anterior cruciate ligament (ACL) reconstruction and whether a correlation exists between return to sports, level of activity and MRI signals.

methodsThe search terms selected for inclusion in the title, abstract, and keyword fields were as follows: 'anterior cruciate ligament' OR 'ACL' AND 'graft maturation' OR 'MRI' AND 'return to sport' OR 'sports activity.' For each study, patient data and the MRI protocol used to assess graft maturation were extracted. An analysis of the correlations between MRI and ACL reconstruction was performed.

resultsA total of 394 patients were included from 7 studies. The mean radiological follow-up was 19.06 ± 11.02 months. Three studies reported no correlations between graft bending angle, signal/noise ratio, signal intensity or Howell score and return to sport. One study revealed that T2* was correlated with return to sport. A further investigation demonstrated that those who were able to regain their preinjury athletic performance exhibited considerably lower ACL/PCL ratio and ACL/muscle ratio of the ACL mid-substance compared to those who were unable to attain the same level of athletic performance. Only one study reported correlations between 12-month SNRs and 60-month Cincinnati, Lysholm and Tegner activity scales, whereas Biercevicz revealed that the combination of volume and the SI predicted the KOOS score at the 5-year follow-up.

conclusionsThere are no reliable radiological parameters available that correlate with return to sport after anterior cruciate ligament reconstruction, but MRI can potentially play a key role in closing this gap. LEVEL OF EVIDENCE: Systematic review of level IV. STUDY REGISTRATION: PROSPERO-CRD42024574365.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionMagnetic Resonance ImagingReturn to SportHumansPredictive Value of TestsAnterior cruciate ligamentGraft maturationMagnetic resonance imagingReturn to sport

Identifiers

PMID40063165
PMCPMC12106503

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.