Evidence map›Paper›PMID 40063289›Full record

ReviewMolecular biology reports2025

New insights into tRNA-derived small RNAs in human digestive diseases.

Yong-Qiang Liu, Feng Chen, Fa Zhang, Yuan-Mei Ye, Yu-Jie Su, Ya-Tao Liu, Yu-Fang Leng

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yong-Qiang Liu *The First Clinical Medical College of Lanzhou University, Lanzhou, 730000, GanSu Province, China.
Feng Chen *Department of Anesthesiology, First Hospital of Lanzhou University, Lanzhou, 730000, GanSu Province, China.
Fa ZhangDepartment of Urology, Gansu Provincial Hospital, Lanzhou, Gansu, China.
Yuan-Mei YeDepartment of Anesthesiology, First Hospital of Lanzhou University, Lanzhou, 730000, GanSu Province, China.
Yu-Jie SuDepartment of Anesthesiology, First Hospital of Lanzhou University, Lanzhou, 730000, GanSu Province, China.
Ya-Tao LiuDepartment of Anesthesiology, First Hospital of Lanzhou University, Lanzhou, 730000, GanSu Province, China.
Yu-Fang LengThe First Clinical Medical College of Lanzhou University, Lanzhou, 730000, GanSu Province, China. lengyf@lzu.edu.cn.ORCID http://orcid.org/0000-0001-7094-2413

Funding

National Natural Science Foundation of China 82260381
6 · The paper itself

Abstract

tRNA-derived small RNAs (tsRNAs) is a type of non-coding RNA that is present in large quantities in humans and exhibits high stability. It plays a crucial role in various physiological processes and diseases. In recent years, research on tsRNAs in tumors has expanded significantly, revealing its regulatory effects in non-neoplastic diseases as well. Additionally, tsRNAs has been extensively studied in the context of digestive system diseases, encompassing both digestive system tumors and non-tumor conditions. It is believed to influence the biological characteristics of diseases as well as clinical pathological features. Given its potential, tsRNAs is anticipated to have broad applications in disease diagnosis and prognosis prediction, and it is expected to emerge as a new class of biomarkers. Nevertheless, numerous issues remain that require in-depth discussion. This article presents an overview of the characteristics and roles of tsRNAs in digestive system diseases, aiming to provide a comprehensive perspective and to inspire new ideas for the diagnosis and treatment of these conditions.

Indexed as

Digestive System DiseasesRNA, Small UntranslatedRNA, TransferDigestive System NeoplasmsHumansRNA, Small UntranslatedRNA, Transferbiological functionclinical significanceDigestive system diseasestsRNAs

Identifiers

PMID40063289

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.