Evidence map›Paper›PMID 40065338›Full record

ArticleBMC surgery2025

Analysis of the efficacy of a prophylactic increasing blood pressure before the end of surgery to reduce postoperative bleeding after gastrectomy: a propensity score-matched analysis.

Guangxu Zhu, Shengjie Zhou, Qihang Sun, Xuren Lu, Qingshun Zhu, Xin Yin, Lei Yu, Jianjun Qu, Xiaomin Lang

Abstract read
In one paragraph

Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guangxu ZhuWeifang People's Hospital, Weifang, Shandong, China.
Shengjie ZhouWeifang People's Hospital, Weifang, Shandong, China.
Qihang SunShandong Second Medical University, Weifang, Shandong, China.
Xuren LuShandong Second Medical University, Weifang, Shandong, China.
Qingshun ZhuWeifang People's Hospital, Weifang, Shandong, China.
Xin YinShandong Second Medical University, Weifang, Shandong, China.
Lei YuWeifang People's Hospital, Weifang, Shandong, China.
Jianjun QuWeifang People's Hospital, Weifang, Shandong, China.
Xiaomin LangWeifang People's Hospital, Weifang, Shandong, China. 344305284@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the efficacy of reducing post-gastrectomy hemorrhage by increasing blood pressure at the end of gastric surgery and to evaluate whether this clinical intervention affects the stability of patients' postoperative circulatory system.

methodsA retrospective analysis was conducted on 499 patients who underwent radical gastrectomy under general anesthesia at our center between January 2023 and January 2024. After 1:1 propensity score matching, the experimental group comprised 157 patients whose operation cavities were examined after increasing blood pressure before the end of gastrectomy, while the control group included 157 patients whose operation cavities were examined using routine procedures without increasing blood pressure.

resultsThe incidences of total postoperative bleeding (0% vs. 3.82%, P = 0.013) and early postoperative bleeding (0% vs. 2.55%, P = 0.044) were significantly lower in the experimental group compared to the control group. There were no significant differences between the two groups in delayed bleeding (0% vs. 1.23%, P = 0.156), systolic blood pressure immediately upon returning to the ward (121.02 ± 18.196 vs. 120.34 ± 21.664, P = 0.795), systolic blood pressure 48 h post-surgery (125.04 ± 16.242 vs. 126.23 ± 17.048, P = 0.529), diastolic blood pressure immediately upon returning to the ward (83.83 ± 11.978 vs. 84.75 ± 12.422, P = 0.506), diastolic blood pressure 48 h post-surgery (74.69 ± 9.773 vs. 75.76 ± 10.605, P = 0.353), heart rate immediately upon returning to the ward (74.31 ± 11.610 vs. 75.15 ± 11.660, P = 0.522), or heart rate 48 h post-surgery (80.49 ± 12.267 vs. 79.11 ± 10.969, P = 0.293). Additionally, there were no statistically significant differences between the two groups regarding anastomotic fistula, intestinal obstruction, postoperative pneumonia, reoperation, mortality, combined organ resection, or postoperative hospital stay (P > 0.05).

conclusionIncreasing blood pressure before the end of gastrectomy can effectively reduce the incidence of primary postoperative hemorrhage without affecting the stability of the perioperative circulatory system.

Indexed as

Blood PressureGastrectomyPostoperative HemorrhageAgedFemaleHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesGastrectomyPostoperative bleedingProphylactic increasing blood pressureTreatment outcome

Identifiers

PMID40065338
PMCPMC11892180

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.