ArticleJournal of inflammation research2025
Association Between Systemic Immune-Inflammatory Indices and Severity of Coronary Artery Lesions in Patients With Coronary Artery Disease in Different Glucose Metabolic States.
Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Preoperative Systemic Immune-Inflammation Index as an Independent Predictor of Postoperative Wound Infection in Diabetic CABG Patients.Journal of cardiovascular development and disease · 2026Article
- Association between triglyceride-glucose index and related indicators with heart failure-related mortality in individuals with early-stage cardiovascular-kidney-metabolic syndrome.Cardiovascular diabetology · 2026Article
- Article
- A study on the correlation between novel inflammatory indices and severity of coronary artery lesions in patients with stable coronary artery disease.Frontiers in cardiovascular medicine · 2026Article
- Post-PCI Inflammation and Diastolic Dysfunction in Patients with Metabolic Risk Factors: A Retrospective Observational Study.Medicina (Kaunas, Lithuania) · 2025Observational
- Association of platelet to high density lipoprotein cholesterol ratio with coronary lesion severity in middle aged and elderly adults.Scientific reports · 2025Article
- Prognostic Impact of Metabolic and Inflammatory Risk for Periprocedural MI and Long-Term Events in Three-Vessel Disease Patients.Journal of inflammation research · 2025Article
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Authors and funding
10 authors.
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Abstract
Background: The systemic immune-inflammatory index (SII) serves as a comprehensive indication of systemic inflammation. However, the relationship between SII and the severity of coronary artery lesions in participants with coronary artery disease (CAD) in different glucose metabolic states has not been fully elucidated. Methods: A total of 2727 patients with CAD were enrolled between January 2018 and April 2022. SII was calculated as (platelet count × neutrophil count)/lymphocyte count. Participants were grouped by SII quartiles. Glucose metabolic status was classified as normal glucose regulation (NGR), pre-diabetes mellitus (Pre-DM) and diabetes mellitus (DM) according to World Health Organization guidelines. Logistic regression and restricted cubic spline models were applied to estimate the relationship between SII and severity of coronary artery lesions in different glucose metabolic states with further adjustments for confounders. Results: Logistic regression analysis indicated a significant association between SII and coronary lesion severity ( Conclusion: The SII is a relatively stable indicator of inflammation and is positively correlated with coronary lesion severity. This study highlights the potential of SII as a novel inflammatory biomarker for assessing the coronary lesion severity among patients in different glucose metabolic states.
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