ReviewHeliyon2025
Pharmaceutical applications of halophilic enzymes.
Review in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Halosimplex yunnanense sp. nov., a novel haloarchaeon from an underground salt mine.Archives of microbiology · 2026Article
- Exploring halophilic microorganisms for novel antimicrobial discovery: molecular mechanisms and computational approaches.Folia microbiologica · 2026Review
- Metabolic adaptations of extremophiles and their applications in environmental biotechnology.World journal of microbiology & biotechnology · 2026Review
- Serine Protease HtrA2 from Halophilic ArcheonBiomolecules · 2026Article
- Complete genome sequence ofMicrobiology resource announcements · 2026Article
- Recent Advances in Understanding Bio-Compounds from Haloarchaea.Journal of microbiology and biotechnology · 2026Review
- Recombinant Expression and Characterization of a New Endogenous and Halophilic GH13_5 Subfamily α-Amylase from Paenibacillus pabuli.Applied biochemistry and biotechnology · 2026Article
- Genomic landscape of biosynthetic gene clusters in Iranian extremophiles reveals prolific metabolite potential, prophage associations, and integrated defensive-metabolic islands.BMC microbiology · 2026Article
- Isolation, screening, and molecular identification of culturable halophilic bacteria with enzymatic and antimicrobial potential from the saline soils of Arzew salt lake, Algeria.Extremophiles : life under extreme conditions · 2025Article
- Halophiles and Halotolerants: From Industry to Astrobiology.Current microbiology · 2025Review
- Review
- Lipase production fromFrontiers in microbiology · 2025Article
- A halophilic metalloprotease fromFrontiers in microbiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Halophiles produce extraordinarily stable enzymes under conditions where conventional enzymes cease to function, denature, and precipitate. Halophilic enzymes have adapted to function optimally at high salt concentrations besides tolerance of organic solvents and thermal stability. These special features offer potential advantages of cost-effectiveness and improved treatment outcomes that make them valuable for pharmaceutical purposes including the synthesis, design, and discovery of new drugs. The article highlights the unique characteristics and adaptation strategies of halophiles towards salinity. It provides an overview of halophilic enzymes' pharmaceutical applications and examines different challenges, opportunities, and recent advances in applying these enzymes in this field.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.