ArticleObesity science & practice2025
Prevalence and Determinants of Elevated High Sensitivity C-Reactive Protein Concentrations in Belgian Children and Adolescents With Overweight or Obesity.
Article in Obesity science & practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Background: Low-grade inflammation, indicated by elevated serum high-sensitivity CRP (hS-CRP), is commonly observed in children and adolescents with overweight or obesity. This study evaluated serum hS-CRP in relation to body fat parameters, lifestyle characteristics, and potential biological determinants (leptin, HDL cholesterol, and 25-OH vitamin D) in a Belgian population. Methods: Anthropometric measurements, biochemical results, and lifestyle questionnaires were analyzed from 267 children and adolescents with overweight or obesity. Results: Median (P10, P90) serum hS-CRP concentration was 1.8 mg/L (0.5, 5.4). In total, 73 subjects had an elevated hS-CRP (≥ 3 mg/L). Children with elevated hS-CRP, irrespective of sex and pubertal status, had higher total body fat mass (BIA) ( Conclusions: A quarter of Belgian children with overweight/obesity have elevated hs-CRP concentrations. This study supports the use of WHtR in clinical practice for the evaluation of children with overweight/obesity, given its association with low-grade inflammation.
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