ArticleFrontiers in physiology2025
The relationship and agreement between systemic and local breakpoints in locomotor and non-locomotor muscles during single-leg cycling.
Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Visually identified breakpoints in muscle oxygen saturation are not equivalent to ventilatory thresholds in national-level triathletes.European journal of applied physiology · 2026Article
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6 authors.
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Abstract
Introduction: There is a well-established relationship between the respiratory compensation point (RCP) and local muscular breakpoints determined from near-infrared spectroscopy (NIRS) and electromyography (EMG). However, these breakpoints have not yet been compared both in locomotor and non-locomotor muscles simultaneously in single-leg cycling exercise. Therefore, the aim of the study was to investigate the relationship and agreement between systemic and local breakpoints in locomotor and non-locomotor muscles. Method: Data from twelve physically-active participants (25.5 ± 3.9 years, 176.1 ± 11.6 cm, 71.2 ± 9.4 kg, 4 females) who completed a continuous single-leg step incremental cycling test (10 W min Results: There was no significant difference in the power output at RCP (127.3 ± 21.8 W) and local muscular breakpoints both from the locomotor (m[HHb]: 119.7 ± 23.6 W, sEMG: 126.6 ± 26.0 W) and non-locomotor (m[HHb]: 117.5 ± 17.9 W, sEMG: 126.1 ± 28.4 W) muscles. Breakpoints also showed significant (p < 0.01) correlations (r = 0.67-0.90, ICC = 0.80-0.94) to each other with weaker correlations in the non-locomotor muscle (r = 0.66-0.86, ICC = 0.74-0.90). Despite the strong correlations, high individual variability and weak limits of agreement (up to -32.5-46.5 W) and substantial absolute differences (10.2-16.7 W) were observed which indicates that these breakpoints cannot be used interchangeably. Discussion: These findings offer further insights into the mechanistic relationship between local and systemic physiological response to exercise with increasing workload. We conclude that, despite strong correlations, local muscular breakpoints do not have to coincide with systemic boundaries of physiological domains.
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