Evidence map›Paper›PMID 40067107›Full record

ReviewRadiology2025

Photon-Counting CT: Technology, Current and Potential Future Clinical Applications, and Overview of Approved Systems and Those in Various Stages of Research and Development.

Fides R Schwartz, Aaron D Sodickson, Perry J Pickhardt, Dushyant V Sahani, Michael H Lev, Rajiv Gupta

Erratum issuedAbstract readReview
In one paragraph

Review in Radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Fides R SchwartzFrom the Department of Radiology, Brigham and Women's Hospital, Boston, Mass (F.R.S., A.D.S.); Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (P.J.P.); Department of Radiology, University of Washington Medicine, Seattle, Wash (D.V.S.); and Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114 (M.H.L., R.G.).ORCID 0000-0002-3598-7082
Aaron D SodicksonFrom the Department of Radiology, Brigham and Women's Hospital, Boston, Mass (F.R.S., A.D.S.); Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (P.J.P.); Department of Radiology, University of Washington Medicine, Seattle, Wash (D.V.S.); and Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114 (M.H.L., R.G.).ORCID 0000-0003-1275-681X
Perry J PickhardtFrom the Department of Radiology, Brigham and Women's Hospital, Boston, Mass (F.R.S., A.D.S.); Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (P.J.P.); Department of Radiology, University of Washington Medicine, Seattle, Wash (D.V.S.); and Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114 (M.H.L., R.G.).ORCID 0000-0002-5534-8202
Dushyant V SahaniFrom the Department of Radiology, Brigham and Women's Hospital, Boston, Mass (F.R.S., A.D.S.); Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (P.J.P.); Department of Radiology, University of Washington Medicine, Seattle, Wash (D.V.S.); and Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114 (M.H.L., R.G.).ORCID 0000-0002-8522-1018
Michael H LevFrom the Department of Radiology, Brigham and Women's Hospital, Boston, Mass (F.R.S., A.D.S.); Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (P.J.P.); Department of Radiology, University of Washington Medicine, Seattle, Wash (D.V.S.); and Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114 (M.H.L., R.G.).
Rajiv GuptaFrom the Department of Radiology, Brigham and Women's Hospital, Boston, Mass (F.R.S., A.D.S.); Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (P.J.P.); Department of Radiology, University of Washington Medicine, Seattle, Wash (D.V.S.); and Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114 (M.H.L., R.G.).ORCID 0000-0002-5882-960X

Funding

Dense Array Image compatible EEG for enhanced neonatal careR01EB024343 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BONMASSAR, GIORGIO · 2017 to 2020
$2.9M
Spectral precision imaging for early diagnosis of colorectal lesions with CT colonographyR01CA212382 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI YOSHIDA, HIROYUKI · 2018 to 2022
$1.5M
A Simulation Framework for X-Ray Phase-Contrast ImagingR03EB032038 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI GUPTA, RAJIV · 2021 to 2021
$179k
NCI NIH HHS R01 CA212382NIBIB NIH HHS R01 EB024343NIBIB NIH HHS R03 EB032038
6 · The paper itself

Abstract

Photon-counting CT (PCCT) has emerged as a transformative technology, with the potential to herald a new era of clinical capabilities. This review provides an overview of the current status and potential future developments of PCCT, including basic physics principles and technical implementation by different vendors, with special attention to applications that have not, to date, been emphasized in the literature. The technologic underpinnings that distinguish PCCT scanners from traditional energy-integrating detector (EID) CT scanners with dual-energy capability are discussed. The inherent challenges of PCCT and the innovative breakthroughs that have enabled key PCCT features, such as enhanced image resolution, material discrimination, and radiation dose efficiency, are reviewed. Two categories of clinical applications are considered:

Indexed as

PhotonsTomography, X-Ray ComputedHumansRadiation Dosage

Identifiers

PMID40067107
PMCPMC11950899

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.