Evidence map›Paper›PMID 40067657›Full record

ArticleEuropean heart journal2025

Oral health benefits and safety of xylitol and potential cardiovascular risk: questioning the validity of the model of Witkowski et al.

Gregory C Valentine, Eva Söderling, Peter Milgrom

Abstract read
In one paragraph

Article in European heart journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Beneficial Effects of Xylitol Chewing Gum and Candies on Oral Health in Older People and Individuals With Disabilities: A Systematic Review.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gregory C ValentineDepartment of Pediatrics, Division of Neonatology at University of Washington, 1959 NE Pacific St. Box 356320, RR542 HSB, Seattle, WA 98195-6320, USA.ORCID 0000-0002-3055-2987
Eva SöderlingInstitute of Dentistry, University of Turku, Turku, Finland.
Peter MilgromDepartment of Oral Health Sciences at University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA.

Funding

Prevention of Developmental Delay and Xylitol (PDDaX) StudyK23HD105929 · NICHD · UNIVERSITY OF WASHINGTON · PI Gregory Charles Valentine · 2022 to 2026
$798k
NIH HHS K23 HD105929
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40067657
PMCPMC12257477

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.