Evidence map›Paper›PMID 40069441›Full record

ArticleInfectious diseases and therapy2025

It's Here, It's There, There's Fungi Everywhere: A Case Series Utilizing Rezafungin for Invasive Candidiasis.

Jacob M Keck, Ryan K Dare, Mitchell B Jenkins, Juan C Rico, Luke Grisham, Jennifer McDonald, Alina Viteri, Robert W Bradsher

Abstract read
In one paragraph

Article in Infectious diseases and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jacob M KeckDepartment of Pharmacy, University of Arkansas for Medical Sciences, 4301 W. Markham St. #529, Little Rock, AR, 72205, USA. jmkeck@uams.edu.ORCID http://orcid.org/0009-0005-1327-8313
Ryan K DareDepartment of Medicine, Division of Infectious Diseases, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Mitchell B JenkinsDepartment of Medicine, Division of Infectious Diseases, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Juan C RicoDepartment of Medicine, Division of Infectious Diseases, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Luke GrishamDepartment of Medicine, Division of Infectious Diseases, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Jennifer McDonaldDepartment of Pharmacy, University of Arkansas for Medical Sciences, 4301 W. Markham St. #529, Little Rock, AR, 72205, USA.
Alina ViteriDepartment of Pharmacy, University of Arkansas for Medical Sciences, 4301 W. Markham St. #529, Little Rock, AR, 72205, USA.
Robert W BradsherDepartment of Medicine, Division of Infectious Diseases, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rezafungin is a long-acting echinocandin with broad coverage against Candida. Rezafungin has primarily been indicated for candidemia, with limited literature available on its use for infections outside of the bloodstream. Herein, three patient cases are presented from an academic medical center. Infectious processes presented include drug-resistant mucosal candidiasis, prosthetic joint infection, and candidemia involving Candida auris. In all three cases, patients received rezafungin. Clinical response was demonstrated in all patients as was tolerability of rezafungin. Together these cases provide further evidence for the use of rezafungin, including its use for treatment of invasive infections other than candidemia.

Indexed as

Candida aurisCandidemiaMucosal candidiasisProsthetic joint infection (PJI)Rezafungin

Identifiers

PMID40069441
PMCPMC11993525

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.