ArticleThe Journal of allergy and clinical immunology2025
Association of daily steps over time with adult asthma incidence.
Article in The Journal of allergy and clinical immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- The effectiveness of physical activity in asthma management: An overview of systematic reviews.PloS one · 2025Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundHigher daily step counts is associated with reduced risk of many chronic diseases. Increased physical activity improves asthma outcomes. There are no known prevention strategies for adult incident asthma.
objectiveWe sought to determine whether objective physical activity affects adult asthma incidence.
methodsParticipants in the All of Us Research Program retrospective cohort aged ≥18 years with linked personal activity tracker and electronic health record data met the inclusion criteria. Asthma was defined as two relevant ICD-9/10 codes and prescription of ≥1 medication. Participants with an asthma diagnosis date before or within 6 months of activity-monitor initiation were assigned to the prevalent asthma group; participants diagnosed after 6 months of activity monitoring were assigned to the incident asthma group.
resultsA total of 8,360 participants were included. Median average steps per day were higher among asthma-free participants (7,795; 95% confidence interval [CI], 5,879-9,921, n = 7,700) than participants with prevalent (6,968; 95% CI, 5,036-9,014, n = 450) or incident (6,953; 95% CI, 5,215-8,261, n = 210) asthma (P < .0001). Significant time-by-incident asthma interaction was observed with a greater decline in steps per day over time in the incident asthma cohort (P = .018). An inverse relationship was observed between average steps per day and asthma incidence after adjusting for age, sex, race, body mass index, major depressive disorder, obstructive sleep apnea, and chronic obstructive lung disease (adjusted hazard ratio, 0.93, 95% CI, 0.88-0.98 per 1,000 average daily step increase).
conclusionsObjectively measured daily steps are lower in adults who develop incident asthma and may represent a modifiable risk factor to reduce asthma incidence. Future studies should objectively monitor physical activity among adults at risk for and with asthma.
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Registered trials
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