Evidence mapPaperPMID 40074255Full record

ArticleBMJ open2025

Association of occupational noise exposure and shift work with non-alcoholic fatty liver disease: a cross-sectional study of male workers in the Chinese automobile manufacturing industry.

Jinwei Zhang, Yuxia Zhang, Cong Xi Qiu, Wenfeng Zeng, Yanmei Ruan, Yunxia Gao, Weiyu Ma, Kangyong Wu, Jingwen Zhang, Jiaxin Cui and 3 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jinwei Zhang *Key Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong, China.
Yuxia Zhang *Key Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong, China.
Cong Xi QiuKey Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong, China.
Wenfeng ZengKey Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong, China.
Yanmei RuanKey Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong, China.
Yunxia GaoSchool of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China.
Weiyu MaKey Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong, China.
Kangyong WuSchool of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China.
Jingwen ZhangSchool of Public Health, Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Jiaxin CuiSchool of Public Health, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Cuiping YeDepartment of Preventive Health, Guangzhou Red Cross Hospital, Guangzhou, Guangdong, China.
Jiabin LiangKey Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong, China.
Zhi WangKey Laboratory of Occupational Environment and Health, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong, China zhi_wang@outlook.com.ORCID http://orcid.org/0000-0002-8415-1759

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to determine the relationship between occupational noise, shift work and non-alcoholic fatty liver disease (NAFLD) in male workers in the automobile manufacturing industry.

designCross-sectional study.

settingThis study was carried out at the Guangzhou Twelfth People's Hospital using data from April to September 2022.

participantsA total of 4672 eligible participants were included in the study. PRIMARY AND SECONDARY OUTCOME MEASURES: Diagnosis of NAFLD was made using ultrasound. Noise was detected according to the Measurement of Physical Factors in the Workplace-Part 8: Noise. Environmental noise intensity was assessed using an EDGE personal noise dosimeter manufactured by CASELLA (UK). The working status of workers was investigated by questionnaire.

resultsThe OR of NAFLD was 1.39 (1.03, 1.88) in the cumulative noise exposure (CNE)≥95 group compared with CNE<85 group. Improved risk of NAFLD in workers with shift work compared with those without shift work (OR=1.35, 95% CI: 1.09, 1.68). As stratified analyses showed, the ORs of NAFLD prevalence related to occupational noise and shift work exposure appear to be increased in young workers. When both shift work and noise exposure work are present simultaneously, the synergy index between them was 0.47 (95% CI: 0.25, 0.89). Combined effects analysis revealed that the OR of NAFLD was 2.02 (95% CI: 1.34, 2.99) in CNE≥95 and cumulative length of night shifts work>2920 hours.

conclusionOccupational noise exposure may be an independent risk factor for NAFLD. It may synergistically affect disease when combined with night shift work, particularly among younger workers. These findings underscore the importance for companies to prioritise the management and training of younger workers, along with targeted occupational health education initiatives, as crucial measures for reducing the incidence of NAFLD.

Indexed as

AutomobilesManufacturing IndustryNoise, OccupationalNon-alcoholic Fatty Liver DiseaseOccupational DiseasesOccupational ExposureShift Work ScheduleAdultChinaCross-Sectional StudiesEast Asian PeopleHumansMaleMiddle AgedPrevalenceRisk FactorsCross-Sectional StudiesEPIDEMIOLOGIC STUDIESOCCUPATIONAL & INDUSTRIAL MEDICINEPUBLIC HEALTHRisk Factors

Identifiers

PMID40074255
PMCPMC11904356

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.