Evidence map›Paper›PMID 40074698›Full record

ArticleAnnals of medicine2025

Clinical characteristics and outcomes of chronic obstructive pulmonary disease patients with family history of chronic airway disease.

Cong Liu, Qing Song, Ya-Ting Peng, Wei Cheng, Ling Lin, Tao Li, Xue-Shan Li, Yu-Qin Zeng, Ai-Yuan Zhou, Yan Chen and 2 more

Abstract read
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In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cong LiuDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Qing SongDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ya-Ting PengDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Wei ChengDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ling LinDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Tao LiDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xue-Shan LiDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yu-Qin ZengDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ai-Yuan ZhouDepartment of Respiratory and Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, China.
Yan ChenDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID 0000-0002-7713-6913
Shan CaiDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ping ChenDepartment of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID 0000-0001-6707-8636

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic Obstructive Pulmonary Disease (COPD) is a heterogeneous condition with different risk factors, including family history. This study aimed to explore association between a family history of chronic airway disease and features and outcomes of COPD.

methodsParticipants were obtained from the RealDTC study between December 2016 and December 2022. Data on demographics, pulmonary function, history of exacerbation at baseline, acute exacerbation during 1-year follow-up and survival status during 3-years follow-up were collected.

results5020 patients were enrolled, with 1307 patients (26.0%) having a family history of chronic airway diseases. Compared with patients without a family history of chronic airway diseases, patients with a family history had a lower forced expiratory Volume in one second (FEV1), higher Modified Medical Research Council (mMRC) score and COPD Assessment Test (CAT) score, higher rate of acute exacerbation and hospitalization in the past year (

conclusionCOPD patients with a family history of chronic airway disease are not rare, and they tend to have more severe symptoms and a higher risk of future deterioration. In the management of COPD, special attention should be paid to patients with a family history of chronic airway disease.

Indexed as

Pulmonary Disease, Chronic ObstructiveAgedDisease ProgressionFemaleFollow-Up StudiesForced Expiratory VolumeHospitalizationHumansMaleMedical History TakingMiddle AgedRespiratory Function TestsRisk Factorsacute exacerbationChronic obstructive pulmonary diseasefamily historyhospitalization

Identifiers

PMID40074698
PMCPMC11905302

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.