ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2025
Major trauma and comorbidity: a scoping review.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Trauma in Pregnancy: A 5-Year Multi-Centre Retrospective Registry Analysis in South Australia.Emergency medicine Australasia : EMA · 2026Article
- Comorbidity Burden and Acute-Care Utilization in Adult Trauma Patients Across the Injury Severity Spectrum in a Nationwide Community-Based Survey (Korea, 2019-2023).Healthcare (Basel, Switzerland) · 2026Article
- The accuracy of the injury severity score in patients below the age of 18 years, a trauma registry data study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Multi-omics analyses reveal novel metabolic signatures of post-traumatic deep vein thrombosis in patients with coronary heart disease.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Biological sex, but not obesity, independently predicts anatomical injury patterns in trauma bay patients: a multivariate retrospective analysis of 2,128 patients.Biology of sex differences · 2026Article
- Establishment of a nomogram for early risk prediction of severe trauma in primary medical institutions: A multi-center study.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025Article
- Trends in Etiology and Mortality in Severe Polytrauma Patients with Traumatic Brain Injury: A 25-Year Retrospective Analysis.Journal of clinical medicine · 2025Article
- Role of blood alcohol level on the risk and severity of trauma recurrence.Trauma surgery & acute care open · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMajor trauma is a leading cause of acute morbidity and mortality. While injury severity drives much of the associated burden, pre-existing comorbidities may influence both acute management and long-term outcomes. This scoping review examines the impact of comorbidities on trauma outcomes.
methodsEmbase, Medline, CINAHL, Cochrane Library, and PubMed were systematically searched from inception to 22/04/2021 (update 22/03/2024). Studies investigating comorbidities as risk factors for adverse outcomes in adults (≥ 18 years) with major trauma were included.
resultsOf 5448 studies identified, 33 met inclusion criteria. No studies examined whether comorbidities increases the risk of major trauma, and only two studies investigated the development of comorbidities post-trauma. Among trauma patients with pre-existing comorbidities particularly cardiovascular disease, diabetes, liver disease, and kidney disease were associated with higher case fatality. Comorbidities were also associated with increased morbidity, longer hospital stays and higher complication rates.
conclusionsTrauma patients with comorbidities suffer experience worse outcomes, yet limited research explores whether comorbidities contribute to trauma risk or emerge as a consequence. Further research is needed to clarify these relationships and guide targeted interventions.
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