Evidence map›Paper›PMID 40075267›Full record

ArticleBMC genomics2025

Genomic analysis reveals population structure and selection signatures in plateau dairy cattle.

Shangzhen Huang, Longgang Ma, Bin Li, Jinhuan Dou, Qing Xu, Yachun Wang

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shangzhen Huang *National Engineering Laboratory for Animal Breeding, Laboratory of Animal Genetics, Breeding and Reproduction, MARA, State Key Laboratory of Animal Biotech Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Longgang Ma *National Engineering Laboratory for Animal Breeding, Laboratory of Animal Genetics, Breeding and Reproduction, MARA, State Key Laboratory of Animal Biotech Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.
Bin LiInstitute of Animal Husbandry and Veterinary Medicine, Academy of Agriculture and Animal Husbandry of Tibet Autonomous Region, Lhasa, 850000, China.
Jinhuan DouAnimal Science and Technology College, Beijing University of Agriculture, Beijing, 102206, China. doujinhuan@bua.edu.cn.
Qing XuInstitute of Life Science and Bioengineering, Beijing Jiaotong University, Beijing, 100044, China. qingxu@bjtu.edu.cn.
Yachun WangNational Engineering Laboratory for Animal Breeding, Laboratory of Animal Genetics, Breeding and Reproduction, MARA, State Key Laboratory of Animal Biotech Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China. wangyachun@cau.edu.cn.

Funding

Special Item of Regional Collaborative Innovation in Tibet Autonomous Region QYXTZX-LS2021-01The earmarked fund for CARS-36 CARS-36the Key Research Project of Tibet Autonomous Region CGZH2023000257The Program for Changjiang Scholar and Innovation Research Team in University IRT_15R62
6 · The paper itself

Abstract

backgroundTo solve the problem of an insufficient supply of dairy products in Tibet, work has been carried out to improve native dairy cattle and introduce purebred dairy cattle from low-altitude areas. The harsh environment of the plateau not only severely limits the production performance of high-yielding dairy cattle, such as Holstein and Jersey cattle, but also challenges their survival. The population structure and plateau adaptation mechanism of plateau dairy cattle are rarely reported. In this study, key genes and pathways affecting plateau purebred and crossbred dairy cattle were explored using genetic chip information.

resultsThe results showed that the genetic diversity of the Tibet dairy cattle population was higher than that of the native cattle and plains dairy cattle. Purebred Holstein and Jersey cattle in Tibet were genetically closer to dairy cattle in the plains, and crossbred dairy cattle were admixed with more Tibet cattle and Apaijiza cattle. Based on the fixation index (F

conclusionsOur results provide a glimpse into diverse selection signatures in plateau dairy cattle, which can be used to enhance our understanding of the genomic basis of plateau adaptation in dairy cattle. These results support further research on breeding strategies such as marker-assisted selection and gene editing in plateau dairy cattle populations.

Indexed as

Genetics, PopulationGenomicsSelection, GeneticAnimalsBreedingCattleDairyingGenetic VariationHaplotypesPolymorphism, Single NucleotideTibetCrossbred cattleHolstein cattlePlateau adaptationPopulation structureSelection signatureTibet native cattle

Identifiers

PMID40075267
PMCPMC11905691

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.