Evidence map›Paper›PMID 40075630›Full record

ArticleCancers2025

Absolute Quantification of Nucleotide Variants in Cell-Free DNA via Quantitative NGS: Clinical Application in Non-Small Cell Lung Cancer Patients.

Guillaume Herbreteau, Marie Marcq, Chloé Sauzay, Maxime Carpentier, Elise Pierre-Noël, Elvire Pons-Tostivint, Audrey Vallée, Sandrine Théoleyre, Acya Bizieux, Jaafar Bennouna and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03926260 (Non-controlled Prospective Pilot Study Assessing Prognostic Performance of Circulating Tumour DNA Kinetic Analysis for Monitoring Response to Treatment of Metastatic Non-small Cell Lung Cancers), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03926260 nacompletednot on this map

Non-controlled Prospective Pilot Study Assessing Prognostic Performance of Circulating Tumour DNA Kinetic Analysis for Monitoring Response to Treatment of Metastatic Non-small Cell Lung Cancers

TypeinterventionalSponsorCentre Hospitalier Departemental VendeeRan2019 to 2022Enrolled100ConditionsMetastatic Non-small Cell Lung CancerArmsctDNA analysis
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Guillaume HerbreteauLaboratory of Biochemistry and Molecular Genetics Platform for Cancer, Nantes University Hospital, 44093 Nantes, France.
Marie MarcqDepartment of Pulmonology, Vendée Regional Hospital, 85000 La Roche sur Yon, France.ORCID 0009-0006-4044-0600
Chloé SauzayLaboratory of Biochemistry and Molecular Genetics Platform for Cancer, Nantes University Hospital, 44093 Nantes, France.
Maxime CarpentierLaboratory of Biochemistry and Molecular Genetics Platform for Cancer, Nantes University Hospital, 44093 Nantes, France.
Elise Pierre-NoëlLaboratory of Biochemistry and Molecular Genetics Platform for Cancer, Nantes University Hospital, 44093 Nantes, France.
Elvire Pons-TostivintThoracic Oncology Department, Nantes University Hospital, 44093 Nantes, France.ORCID 0000-0003-4478-0523
Audrey ValléeLaboratory of Biochemistry and Molecular Genetics Platform for Cancer, Nantes University Hospital, 44093 Nantes, France.ORCID 0000-0003-1613-281X
Sandrine ThéoleyreLaboratory of Biochemistry and Molecular Genetics Platform for Cancer, Nantes University Hospital, 44093 Nantes, France.
Acya BizieuxDepartment of Pulmonology, Vendée Regional Hospital, 85000 La Roche sur Yon, France.
Jaafar BennounaFoch Hospital, 92150 Suresnes, France.
Marc G DenisLaboratory of Biochemistry and Molecular Genetics Platform for Cancer, Nantes University Hospital, 44093 Nantes, France.ORCID 0000-0001-5865-3248

Funding

Centre Hospitalier Universitaire de Nantes & CHD Vendée RC19_0208
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ctDNAdPCRNGSNSCLCquantification

Identifiers

PMID40075630
PMCPMC11898635

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.