Evidence mapPaperPMID 40075725Full record

ReviewCancers2025

Advancing Cancer Therapy with Quantum Dots and Other Nanostructures: A Review of Drug Delivery Innovations, Applications, and Challenges.

Ashutosh Pareek, Deepanjali Kumar, Aaushi Pareek, Madan Mohan Gupta

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ashutosh PareekDepartment of Pharmacy, Banasthali Vidyapith, Banasthali 304022, India.ORCID 0000-0002-4781-4867
Deepanjali KumarDepartment of Pharmacy, Banasthali Vidyapith, Banasthali 304022, India.
Aaushi PareekDepartment of Pharmacy, Banasthali Vidyapith, Banasthali 304022, India.
Madan Mohan GuptaSchool of Pharmacy, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.ORCID 0000-0002-5224-4774

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotechnology, particularly quantum dots (QDs), has ushered in a transformative era in the pharmaceutical and medical industries, offering notable opportunities for nanoscale advancements. These nanoscale particles, known for their exceptional optical properties and quantum confinement, have emerged as indispensable tools in cancer drug delivery and bioimaging. This review delves into various drug conjugation techniques with QDs, including covalent linking, non-covalent conjugation, click chemistry, disulfide linkage, and pH-sensitive linkage. Each method provides distinct advantages, such as enhanced stability, reversibility, specificity, and controlled drug release. Moreover, QDs have demonstrated significant promise in oncology by efficiently delivering drugs to cancerous tissues while minimising systemic toxicity. Investigations into their applications in different cancers, such as blood, brain, cervical, breast cancers, etc., reveal their efficacy in targeted drug delivery, real-time imaging, and improved therapeutic outcomes. However, challenges such as potential toxicity, stability, pharmacokinetics, and targeting specificity must be addressed to fully harness the benefits of QDs in cancer therapy. Future research should focus on developing biocompatible QDs, optimising conjugation techniques, and elucidating their safety profiles and long-term effects in biological systems. Overall, QDs represent a promising frontier in cancer treatment, offering multifaceted capabilities that hold the potential for enhanced therapeutic outcomes and reduced side effects across various cancers.

Indexed as

bioimagingbreast cancerdrug deliveryfluorescencequantum dots

Identifiers

PMID40075725
PMCPMC11898779

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.