Evidence map›Paper›PMID 40076185›Full record

ArticlePolymers2025

Development and Characterization of Antimicrobial Chitosan/Polyethylene Oxide/Bacterial Cellulose Nanofibers.

Fatma Sude Cetin, Tubanur Avci, Emre Uygur, Elif Ilhan, Elif Kaya, Gulgun Bosgelmez Tinaz, Liviu Duta, Canan Dogan, Oguzhan Gunduz

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Chitosan/PEO Nanofibers as a Delivery Platform for Sustained Release ofInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fatma Sude CetinCenter for Nanotechnology and Biomaterials Application and Research (NBUAM), Marmara University, Istanbul 34722, Turkey.ORCID 0000-0003-2361-0728
Tubanur AvciCenter for Nanotechnology and Biomaterials Application and Research (NBUAM), Marmara University, Istanbul 34722, Turkey.ORCID 0000-0002-7289-1020
Emre UygurCenter for Nanotechnology and Biomaterials Application and Research (NBUAM), Marmara University, Istanbul 34722, Turkey.
Elif IlhanCenter for Nanotechnology and Biomaterials Application and Research (NBUAM), Marmara University, Istanbul 34722, Turkey.ORCID 0000-0001-7253-8270
Elif KayaDepartment of Biochemistry, Health Sciences Institute, Marmara University, Istanbul 34854, Turkey.
Gulgun Bosgelmez TinazDepartment of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Marmara University, Istanbul 34668, Turkey.ORCID 0000-0003-1080-4419
Liviu DutaNational Institute for Laser, Plasma and Radiation Physics, 409 Atomistilor Street, 077125 Magurele, Romania.ORCID 0000-0002-6408-6056
Canan DoganCenter for Nanotechnology and Biomaterials Application and Research (NBUAM), Marmara University, Istanbul 34722, Turkey.ORCID 0000-0002-6817-3392
Oguzhan GunduzCenter for Nanotechnology and Biomaterials Application and Research (NBUAM), Marmara University, Istanbul 34722, Turkey.ORCID 0000-0002-4926-6489

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study introduces novel chitosan (CS) and polyethylene oxide (PEO) copolymers reinforced with bacterial cellulose (BC) to fabricate nanofibers using the electrospinning method. SEM analysis confirmed uniform nanofiber formation, with CS/PEO/BC nanofibers (~240 nm) exhibiting a larger diameter than CS/PEO ones (~190 nm). FTIR spectroscopy confirmed BC integration, while Differential scanning calorimetry analysis indicated minimal impact on glass transition temperature. Notably, as compared to CS/PEO nanofibers, the CS/PEO/BC ones demonstrated superior swelling capacity, accelerated biodegradation, and enhanced mechanical (i.e., tensile) properties, with maximum stress and strain values of ~3.41 MPa and ~0.01% vs. ~2.14 MPa and ~0.01%. Antimicrobial assays confirmed activity against bacterial strains, and biocompatibility tests showed high cell viability at day seven (99.26% for CS/PEO/BC nanofibers). These findings highlight the potential of CS/PEO/BC nanofibers as promising candidates for tissue engineering, offering improved strength, biodegradability, and antimicrobial properties.

Indexed as

antimicrobial efficiencybacterial cellulosebiocompatibility testingbiomaterialelectrospinning

Identifiers

PMID40076185
PMCPMC11902829

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.