Evidence map›Paper›PMID 40076312›Full record

ArticleMolecules (Basel, Switzerland)2025

Simultaneous Quantification of Bioactive Triterpene Saponins Calenduloside E and Chikusetsusaponin IVa in Different Plant Parts of Ten Amaranthaceae Species by UPLC-ESI-MS/MS Method.

Karolina Grabowska, Paweł Żmudzki, Agnieszka Galanty, Irma Podolak

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Saponins fromMolecules (Basel, Switzerland) · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karolina GrabowskaDepartment of Pharmacognosy, Jagiellonian University Medical College, 9 Medyczna Str., 30-688 Cracow, Poland.ORCID 0000-0002-1426-2218
Paweł ŻmudzkiDepartment of Medicinal Chemistry, Jagiellonian University Medical College, 9 Medyczna Str., 30-688 Cracow, Poland.ORCID 0000-0003-3594-1241
Agnieszka GalantyDepartment of Pharmacognosy, Jagiellonian University Medical College, 9 Medyczna Str., 30-688 Cracow, Poland.ORCID 0000-0001-5636-8646
Irma PodolakDepartment of Pharmacognosy, Jagiellonian University Medical College, 9 Medyczna Str., 30-688 Cracow, Poland.ORCID 0000-0002-1251-7192

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calenduloside E (CE) and chikusetsusaponin IVa (ChIVa) are triterpene saponins with multidirectional bioactivity. In this study, the contents of CE and ChIVa were determined in the roots, stems, leaves, and fruits of ten wild-growing species of Amaranthaceae. To achieve optimal extraction conditions for both saponins, maceration, shaking-assisted maceration, and ultrasound-assisted and heat reflux extraction were compared. A sensitive, specific, and rapid UPLC-MS/MS method was developed and validated for the simultaneous quantification of CE and ChIVa. The results showed that CE and ChIVa coexisted in most of the species analyzed, except for

Indexed as

AmaranthaceaeOleanolic AcidSaponinsTriterpenesChromatography, High Pressure LiquidPlant ExtractsPlant RootsSpectrometry, Mass, Electrospray IonizationTandem Mass Spectrometrychikusetsu saponin IVaOleanolic AcidPlant ExtractsSaponinsTriterpenesAmaranthaceaeAtriplexBlitumcalenduloside EChenopodiumchikusetsusaponin IVaOxybasisquantificationtriterpene saponinsUPLC-MS/MS

Identifiers

PMID40076312
PMCPMC11901714

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.