Evidence map›Paper›PMID 40076340›Full record

ArticleMolecules (Basel, Switzerland)2025

Synthesis and Evaluation of Boron-Containing Heterocyclic Compounds with Antimicrobial and Anticancer Activities.

João Lucas Bruno Prates, Samanta de Matos Silva, Kaila Petrolina Medina-Alarcón, Kelvin Sousa Dos Santos, Jenyffie Araujo Belizario, Juliana Romano Lopes, Freddy Humberto Marin-Dett, Debora Leite Campos, Maria José Soares Mendes Giannini, Ana Marisa Fusco-Almeida and 3 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

João Lucas Bruno PratesSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.
Samanta de Matos SilvaSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.ORCID 0000-0002-1390-117X
Kaila Petrolina Medina-AlarcónSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.
Kelvin Sousa Dos SantosSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.ORCID 0000-0001-8328-9054
Jenyffie Araujo BelizarioSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.
Juliana Romano LopesSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.
Freddy Humberto Marin-DettSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.ORCID 0000-0002-6979-625X
Debora Leite CamposSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.
Maria José Soares Mendes GianniniSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.ORCID 0000-0002-8059-0826
Ana Marisa Fusco-AlmeidaSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.
Paula Aboud BarbugliSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.
Fernando Rogério PavanSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.ORCID 0000-0002-6969-3963
Jean Leandro Dos SantosSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil.ORCID 0000-0002-2460-2829

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Finance Code 001Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2019/07574-9Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2023/05739-6
6 · The paper itself

Abstract

Organoboron compounds, especially those containing boronic acid and benzoxaborole in their structure, have been gaining prominence in medicinal chemistry, following the FDA approval of tavaborole for the treatment of onychomycosis and bortezomib for multiple myeloma. The antimicrobial and anticancer effects of organoboron compounds motivate the investigation of the effects of the novel derivatives described here. A total of fourteen new boronic derivatives were synthesized and characterized using analytical methods. The antimicrobial activities were evaluated against

Indexed as

Anti-Infective AgentsAntineoplastic AgentsBoronBoron CompoundsHeterocyclic CompoundsAntifungal AgentsCandida albicansCell Line, TumorHumansMicrobial Sensitivity TestsMolecular StructureMycobacterium tuberculosisStructure-Activity RelationshipAntifungal AgentsAnti-Infective AgentsAntineoplastic AgentsBoronBoron CompoundsHeterocyclic Compoundsantimicrobialbenzoxaboroleboron-containing compoundsboronic acidcancerfungiMycobacterium tuberculosisorganoboron

Identifiers

PMID40076340
PMCPMC11901438

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.