Evidence mapPaperPMID 40076485Full record

ArticleInternational journal of molecular sciences2025

Plasma Atrial Natriuretic Peptide Predicts Oxidized Low-Density Lipoprotein Levels in Type 2 Diabetes Mellitus Patients Independent of Circulating Adipokine and Cytokine.

Ahmed Bakillah, Maram Al Subaiee, Ayman Farouk Soliman, Khamis Khamees Obeid, Shahinaz Faisal Bashir, Arwa Al Hussaini, Mohammad Al Arab, Abeer Al Otaibi, Sindiyan Al Shaikh Mubarak, Ali Ahmed Al Qarni

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ahmed BakillahKing Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Mubarraz 36428, Saudi Arabia.ORCID 0000-0001-5434-1976
Maram Al SubaieeMinistry of National Guard-Health Affairs (MNGHA), King Abdulaziz Hospital, Al Mubarraz 36428, Saudi Arabia.
Ayman Farouk SolimanMinistry of National Guard-Health Affairs (MNGHA), King Abdulaziz Hospital, Al Mubarraz 36428, Saudi Arabia.
Khamis Khamees ObeidMinistry of National Guard-Health Affairs (MNGHA), King Abdulaziz Hospital, Al Mubarraz 36428, Saudi Arabia.
Shahinaz Faisal BashirKing Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Mubarraz 36428, Saudi Arabia.
Arwa Al HussainiKing Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Mubarraz 36428, Saudi Arabia.
Mohammad Al ArabKing Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Mubarraz 36428, Saudi Arabia.
Abeer Al OtaibiKing Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Mubarraz 36428, Saudi Arabia.ORCID 0009-0000-6437-3074
Sindiyan Al Shaikh MubarakKing Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Mubarraz 36428, Saudi Arabia.
Ali Ahmed Al QarniKing Abdullah International Medical Research Center (KAIMRC), Eastern Region, Al Mubarraz 36428, Saudi Arabia.

Funding

King Abdullah International Medical Research Center (KAIMRC) RA-18/021A (PI: Ahmed Bakillah)
6 · The paper itself

Abstract

Atrial natriuretic peptide (ANP) and oxidized low-density lipoprotein (ox-LDL) play essential roles in the development and progression of vascular complications associated with type 2 diabetes mellitus (T2DM), and both are independently linked to cardiovascular diseases (CVD). However, the relationship between ANP and ox-LDL in patients with T2DM remains unclear as previous studies have primarily focused on circulating levels in various diseases. This study investigated the relationship between ANP and ox-LDL levels in obese individuals with T2DM. The cohort included 57 patients with T2DM (mean age 61.14 ± 9.99 years; HbA1c 8.66 ± 1.60%; BMI 35.15 ± 6.65 kg/m

Indexed as

AdipokinesAtrial Natriuretic FactorCytokinesDiabetes Mellitus, Type 2Lipoproteins, LDLAgedBiomarkersFemaleHumansMaleMiddle AgedObesityAdipokinesAtrial Natriuretic FactorBiomarkersCytokinesLipoproteins, LDLoxidized low density lipoproteinadipokinesANPcoronary artery diseasecytokinesdyslipidemiaendothelial dysfunctioninflammationinsulin resistanceobesityox-LDLtype 2 diabetesvascular complications

Identifiers

PMID40076485
PMCPMC11899485

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.