Evidence map›Paper›PMID 40076542›Full record

SynthesisInternational journal of molecular sciences2025

Influence of Klotho Protein Levels in Obesity and Sarcopenia: A Systematic Review.

Diana G Ariadel-Cobo, Brisamar Estébanez, Elena González-Arnáiz, María Pilar García-Pérez, Marta Rivera-Viloria, Begoña Pintor de la Maza, David Emilio Barajas-Galindo, Diana García-Sastre, María D Ballesteros-Pomar, María J Cuevas

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Anti-aging effects of glycyrrhizin via maintaining Klotho levels.Journal of clinical biochemistry and nutrition · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Diana G Ariadel-CoboInstitute of Biomedicine (IBIOMED), University of León, 24071 León, Spain.
Brisamar EstébanezInstitute of Biomedicine (IBIOMED), University of León, 24071 León, Spain.ORCID 0000-0001-5034-9508
Elena González-ArnáizInstitute of Biomedicine (IBIOMED), University of León, 24071 León, Spain.ORCID 0000-0001-8124-6042
María Pilar García-PérezDepartment of Endocrinology and Nutrition, Complejo Asistencial Universitario de León (CAULE), 24071 León, Spain.
Marta Rivera-ViloriaInstitute of Biomedicine (IBIOMED), University of León, 24071 León, Spain.ORCID 0000-0003-2109-1338
Begoña Pintor de la MazaDepartment of Endocrinology and Nutrition, Complejo Asistencial Universitario de León (CAULE), 24071 León, Spain.
David Emilio Barajas-GalindoDepartment of Endocrinology and Nutrition, Complejo Asistencial Universitario de León (CAULE), 24071 León, Spain.
Diana García-SastreDepartment of Endocrinology and Nutrition, Complejo Asistencial Universitario de León (CAULE), 24071 León, Spain.ORCID 0009-0006-3916-4661
María D Ballesteros-PomarInstitute of Biomedicine (IBIOMED), University of León, 24071 León, Spain.ORCID 0000-0002-5729-9926
María J CuevasInstitute of Biomedicine (IBIOMED), University of León, 24071 León, Spain.ORCID 0000-0002-9122-8443

Funding

Gerencia Regional de Salud, Castilla y León, Spain GRS 2326/A/21 and GRS 2516/A/22
6 · The paper itself

Abstract

The

Indexed as

GlucuronidaseKlotho ProteinsObesitySarcopeniaFibroblast Growth Factor-23Fibroblast Growth FactorsHumansFGF23 protein, humanFibroblast Growth Factor-23Fibroblast Growth FactorsGlucuronidaseKlotho ProteinsKL protein, humanadipose tissueFGFinflammagingKlothosarcopenic obesity

Identifiers

PMID40076542
PMCPMC11900336

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.