ReviewInternational journal of molecular sciences2025
Therapeutic Perspectives of Aminoflavonoids-A Review.
Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Myriad aryne derivatives from carboxylic acids.Nature · 2026Article
- Special Issue: Discovery of Bioactive Phytochemicals' Molecular Mechanisms Against Different Diseases Based on Network Pharmacology and Molecular Docking.International journal of molecular sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Natural compounds containing nitrogen are a source of many biologically active molecules used as drugs. Due to their multidirectional effects, they represent effective therapeutic compounds in many medical areas. Flavonoids, as well as their bioprecursors, chalcones, that occur in plants possess a number of medicinal benefits. Their synthetic amino derivatives constitute a large group of compounds that exhibit pharmacological activity. Due to the increasing level of drug resistance among patients, new therapeutic agents and options are urgently needed. Therefore, aminoflavonoids may be a promising source of new drugs. In this review, the biological activities of flavonoids, including chalcones, with complexes containing a nitrogen atom and the aminoflavones Ru and Pt are summarized. The purpose of this review is to provide an overview of the synthesis and pharmacological activity of aminoflavonoids and to show how synthetic modifications of these compounds can influence their biological activities. It covers the most recent reports on obtaining aminoflavones, aminochalcones, and their derivatives, along with information about their anticancer, antimicrobial, antimalarial, antiviral, and anti-inflammatory activities.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.