Evidence map›Paper›PMID 40076863›Full record

ArticleInternational journal of molecular sciences2025

Astaxanthin Alleviates Oxidative Stress in Mouse Preantral Follicles and Enhances Follicular Development Through the AMPK Signaling Pathway.

Jiaqi He, Yue Zhong, Yaqiu Li, Sitong Liu, Xiaoyan Pan

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiaqi HeCenter for Reproductive Medicine, Jilin Medical University, Jilin 132013, China.
Yue ZhongCenter for Reproductive Medicine, Jilin Medical University, Jilin 132013, China.
Yaqiu LiCenter for Reproductive Medicine, Jilin Medical University, Jilin 132013, China.
Sitong LiuCenter for Reproductive Medicine, Jilin Medical University, Jilin 132013, China.
Xiaoyan PanCenter for Reproductive Medicine, Jilin Medical University, Jilin 132013, China.ORCID 0000-0001-7357-090X

Funding

the Innovation and Entrepreneurship Training Program of Jilin Medical University 202413706004the Scientific and Technological Research Project of Jilin Province 20240305074YY
6 · The paper itself

Abstract

This study investigates the effects of astaxanthin on oxidative stress, mitochondrial function, and follicular development in mouse preantral follicles, with a focus on the involvement of the adenosine monophosphate-activated protein kinase (AMPK) signaling pathway. Astaxanthin (2.5 nM) significantly enhanced both the antrum formation (from 85.96% in the control group to 94.38% in the astaxanthin group) and maturation rates (from 79.15% to 85.12%) of oocytes (

Indexed as

AMP-Activated Protein KinasesOvarian FollicleOxidative StressSignal TransductionAnimalsApoptosisFemaleMiceMitochondriaOocytesReactive Oxygen SpeciesXanthophyllsAMP-Activated Protein KinasesastaxanthineReactive Oxygen SpeciesXanthophyllsastaxanthinin vitro culturemitochondriaoxidative stresspreantral follicles

Identifiers

PMID40076863
PMCPMC11900623

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.