Evidence map›Paper›PMID 40076866›Full record

ArticleInternational journal of molecular sciences2025

Intronic

Michał Ambroziak, Jakub Franke, Anna Wójcicka, Monika Kolanowska, Tomasz Jaxa-Chamiec, Andrzej Budaj

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michał AmbroziakDepartment of Cardiology, Centre of Postgraduate Medical Education, Grochowski Hospital, 04-073 Warsaw, Poland.ORCID 0000-0002-3172-0719
Jakub FrankeWarsaw Genomics, 02-502 Warsaw, Poland.ORCID 0000-0002-2661-1446
Anna WójcickaWarsaw Genomics, 02-502 Warsaw, Poland.
Monika KolanowskaWarsaw Genomics, 02-502 Warsaw, Poland.ORCID 0000-0003-3457-0557
Tomasz Jaxa-ChamiecDepartment of Cardiology, Centre of Postgraduate Medical Education, Grochowski Hospital, 04-073 Warsaw, Poland.
Andrzej BudajDepartment of Cardiology, Centre of Postgraduate Medical Education, Grochowski Hospital, 04-073 Warsaw, Poland.

Funding

Centre of Postgraduate Medical Education 501-1-10-14-20
6 · The paper itself

Abstract

Premature myocardial infarction (MI) risk factors, including genetic ones, are crucial for an individual risk stratification. The aim of this study was to investigate the role of genetic variants in young patients with MI and a family history of premature atherosclerosis (FHpa). The studied group consisted of 70 patients aged 26-49 (mean 43.1, SD ± 4.3; 17 women, 53 men), with MI and with FHpa. The targeted enrichment library was prepared and analyzed using the Next-Generation Sequencing method. The results of sequencing were compared to data from the reference control population, consisting of 597 people with no history of MI (418 women, 179 men) aged 18-83 (mean 40.5, SD ± 12.4), using Propensity Score Matching.

Indexed as

AtherosclerosisCytoskeletal ProteinsGenetic Predisposition to DiseaseMyocardial InfarctionNerve Tissue ProteinsNuclear ProteinsAdolescentAdultAgedAged, 80 and overCase-Control StudiesFemaleHumansMaleMiddle AgedPolandCytoskeletal ProteinsNerve Tissue ProteinsNuclear ProteinsSYNE1 protein, humancoronary artery diseasemyocardial infarctionmyocardial infarction at young agepremature coronary artery diseaseSYNE1

Identifiers

PMID40076866
PMCPMC11899963

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.