Evidence mapPaperPMID 40077425Full record

ArticleFoods (Basel, Switzerland)2025

Indole Content Profiling During Biological Ageing of Cava Sparkling Wine.

Clara Abarca-Rivas, Alba Martín-García, Montserrat Riu-Aumatell, Elvira López-Tamames

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. What Can Fluorescence Tell Us About Wine?International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Clara Abarca-RivasPolyphenol Research Group, Department of Nutrition, Food Science and Gastronomy, XIA, Faculty of Pharmacy and Food Sciences, Institute of Nutrition and Food Safety (INSA-UB), CCNIEC Research Group "Antioxidants Naturals: Polifenols", University of Barcelona, 08028 Barcelona, Spain.ORCID 0009-0001-7487-1007
Alba Martín-GarcíaAroma, and Food Quality Factors Group, Department of Nutrition, Food Science and Gastronomy, XIA, Faculty of Pharmacy and Food Sciences, Institute of Nutrition and Food Safety (INSA-UB), CCNIEC Research Group "Aroma and Food Quality Factors Group", University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0002-2185-5468
Montserrat Riu-AumatellAroma, and Food Quality Factors Group, Department of Nutrition, Food Science and Gastronomy, XIA, Faculty of Pharmacy and Food Sciences, Institute of Nutrition and Food Safety (INSA-UB), CCNIEC Research Group "Aroma and Food Quality Factors Group", University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-7269-4732
Elvira López-TamamesAroma, and Food Quality Factors Group, Department of Nutrition, Food Science and Gastronomy, XIA, Faculty of Pharmacy and Food Sciences, Institute of Nutrition and Food Safety (INSA-UB), CCNIEC Research Group "Aroma and Food Quality Factors Group", University of Barcelona, 08028 Barcelona, Spain.

Funding

Generalitat de Catalunya AGL2016-78324ICIU/AEI/10.13039/501100011033 and FSE+ PRE2022-104187MICIN/AEI/FEDER, UE CEX2021-001234-M
6 · The paper itself

Abstract

Indoles are bioactive components found in wine products and are associated with yeast activity. Cava, a Spanish sparkling wine, is characterized by aging in contact with lees, making it a potential matrix for indoles. Therefore, the aim of this study was to determine the indole content in Cava produced at an industrial scale. Nine indoles were analysed by Ultra High-Performance Liquid Chromatography-Tandem Mass Spectrometry in Cava samples with different ageing times (n = 74). Significant amounts of tryptophan (2.3-1680.4 μg/L), tryptophan ethyl ester (0.1-5.2 μg/L), 5-methoxytryptophol (0.3-29.2 µg/L) and n-acetyl serotonin (0.3-2.3 μg/L) were determined. Tryptophan and tryptophan ethyl ester were positively correlated and decreased with ageing time. In fact, a concentration of less than 0.56 μg of the latter indole can become a marker of the most aged Cavas. The ageing time in contact with lees seems to play a key role affecting the indole content, since base wines show high amount of tryptophan and tryptophan ethyl ester while aged sparkling wines have values around the lower 95% confidence limit. Notably, the identification of tryptophan ethyl ester as a potential marker for aging in Cava suggests a new avenue for further research and quality assessment in its production.

Indexed as

indolemelatoninsparkling winetryptophan ethyl esterUHPLC-MS/MS

Identifiers

PMID40077425
PMCPMC11899149

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.