Evidence mapPaperPMID 40077591Full record

ArticleFoods (Basel, Switzerland)2025

Sex-Specific Biochemical and Histopathological Effects of Chronic Meat-Based vs. Plant-Based Burger Consumption in a Rodent Model.

Cristina Filip, Ruxandra Ștefănescu, Bianca-Eugenia Ősz, Amalia Pușcaș, Corneliu Tanase, Adela Nechifor-Boilă, Amelia Tero-Vescan

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cristina FilipDepartment of Biochemistry, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 38th Gh. Marinescu Street, 540139 Târgu Mureş, Romania.
Ruxandra ȘtefănescuDepartment of Pharmacognosy and Phytotherapy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 38th Gh. Marinescu Street, 540139 Târgu Mureş, Romania.ORCID 0000-0002-3346-3867
Bianca-Eugenia ŐszDepartment of Pharmacology and Clinical Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 38th Gh. Marinescu Street, 540139 Târgu Mureş, Romania.
Amalia PușcașDepartment of Biochemistry, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 38th Gh. Marinescu Street, 540139 Târgu Mureş, Romania.
Corneliu TanaseDepartment of Pharmaceutical Botany, Research Center of Medicinal and Aromatic Plants, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 38th Gh. Marinescu Street, 540139 Târgu Mureş, Romania.ORCID 0000-0002-5900-743X
Adela Nechifor-BoilăDepartment of Histology, Center for Advanced Medical and Pharmaceutical Research, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 38th Gh. Marinescu Street, 540139 Târgu Mureş, Romania.ORCID 0000-0002-1165-0071
Amelia Tero-VescanDepartment of Biochemistry, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 38th Gh. Marinescu Street, 540139 Târgu Mureş, Romania.ORCID 0009-0000-9704-869X

Funding

George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș Grant number No.164/14/10.01.2023
6 · The paper itself

Abstract

The growing consumption of processed foods, including meat-based and plant-based burgers (PBM), raises concerns about their long-term health effects. While PBM burgers are marketed as healthier alternatives, their biochemical and histological impacts remain unclear. This study investigates the effects of chronic meat-based and PBM burger consumption on metabolic and organ health, considering sex differences. Thirty-six Wistar rats (18 males and 18 females) were divided into three groups: control (standard chow), meat burger-fed, and PBM burger-fed. Improved chow was prepared using lyophilized burger powder. Over eight weeks, food intake, weight gain, and food efficiency ratio (FER) were monitored. Serum biochemical markers, including AST, ALT, urea, creatinine, lipid profile (TG, CHOL, HDL, LDL), and leptin, were analyzed, alongside histopathological evaluation of the liver, kidneys, and heart. PBM-fed rats exhibited significantly higher FER than the meat group (

Indexed as

biochemical markershistopathologyleptin resistancelipid profileliver functionmetabolic healthplant-based meatprocessed foodsex differences

Identifiers

PMID40077591
PMCPMC11898711

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.