Evidence map›Paper›PMID 40078501›Full record

ReviewTransplant international : official journal of the European Society for Organ Transplantation2025

Evaluating Risk in Kidney Living Donors.

Fernanda Ortiz, Lorna Marson, Rachel Thomas, Andreas Kousios, Elvana Rista, Carmen Lefaucheur, Sanem Cimen, David Cucchiari, Gianluigi Zaza, Lucrezia Furian and 1 more

Abstract readReview
In one paragraph

Review in Transplant international : official journal of the European Society for Organ Transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Transplant International: Looking Back at 2025, Looking Forward to 2026.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  7. Kidney Transplantation in Western Balkans: A Regional Blueprint for Access, Capacity, and Equity.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fernanda OrtizAbdominal Unit, Nephrology, Helsinki University Hospital, Helsinki, Finland.
Lorna MarsonEdinburgh Transplant Centre, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
Rachel ThomasEdinburgh Transplant Centre, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
Andreas KousiosSchool of Medicine, European University of Cyprus, Engomi, Cyprus.
Elvana RistaDepartment of Nephrology, Dialysis, and Kidney Transplantation, Hygeia International Hospital, Tirana, Albania.
Carmen LefaucheurSaint Louis Hospital, Assistance Publique- Hopiteux de Paris and Université Paris Cité, Paris, France.
Sanem CimenDepartment of General Surgery, Sağlık Bilimleri Üniversitesi, Ankara, Türkiye.
David CucchiariRenal Transplant Unit, Department of Nephrology and Kidney Transplantation, Hospital Clínic, Barcelona, Spain.
Gianluigi ZazaNephrology, Dialysis and Renal Transplant Unit, Department of Pharmacy, Health and Nutritional Sciences, University of Calabria Rende, Calabria, Italy.
Lucrezia FurianKidney and Pancreas Transplantation Unit, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padova, Padova, Italy.
Baris AkinDepartment of General Surgery, Demiroglu Bilim University and Group Florence Nightingale Hospital, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney donation is a safe procedure for carefully screened donors. The growing shortage of organs and improved survival rates among recipients of living donor transplants have broadened the criteria for acceptable living donors, including older individuals and those with pre-existing health conditions. Consequently, ensuring both the short- and long-term safety of living donors is of paramount importance. The primary objectives are to prevent the need for kidney replacement therapy, major cardiovascular events, or premature death. Lifelong monitoring of living donors is essential to facilitate early treatment for preventable illnesses. To this end, annual follow-up is generally recommended, which should minimally include an assessment of blood pressure, body mass index, kidney function, albuminuria, lifestyle factors, and general wellbeing. However, the management of these risk factors and treatment targets in this population remain inadequately defined. Recommendations for genetic counseling in cases of living-related donation also remain inconsistent. The aim of this mini-review is to address the challenges in evaluating the evidence on the long-term consequences of kidney donation, particularly concerning the risk of developing end-stage kidney disease, cardiovascular mortality, gestational complications, and hypertension. This article aligns with the ESOT call for action to promote living kidney donation and EKITA's mission.

Indexed as

Kidney TransplantationLiving DonorsNephrectomyCardiovascular DiseasesFemaleHumansHypertensionKidney Failure, ChronicPregnancyRisk AssessmentRisk Factorscardiovascular diseaseend-stage kidney diseasehypertensionkidney transplantliving donor

Identifiers

PMID40078501
PMCPMC11896807

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.