Review in Arteriosclerosis, thrombosis, and vascular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors.
Alan DaughertyDepartment of Physiology, Saha Cardiovascular Research Center, Saha Aortic Center, University of Kentucky (A.D., H.S.).ORCID 0000-0003-2093-3775
Dianna M MilewiczDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston (D.M.M., Z.Z.).ORCID 0000-0002-7806-0068
David A DichekDivision of Cardiology, Department of Medicine, University of Washington, Seattle (D.A.D.).ORCID 0000-0002-5224-2736
Ketan B GhaghadaDepartment of Radiology, Texas Children's Hospital, Houston (K.B.G.).ORCID 0000-0003-1012-8668
Jay D HumphreyDepartment of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.).ORCID 0000-0003-1011-2025
Scott A LeMaireDivision of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery and Cardiovascular Research Institute (S.A.L., Y.L., Y.H.S.), Baylor College of Medicine, Houston, TX.
Yanming LiDivision of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery and Cardiovascular Research Institute (S.A.L., Y.L., Y.H.S.), Baylor College of Medicine, Houston, TX.ORCID 0000-0002-8213-9166
Ziad MallatDivision of Cardiorespiratory Medicine, Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, United Kingdom (Z.M.).ORCID 0000-0003-0443-7878
Yvan SaeysData Mining and Modelling for Biomedicine, VIB Center for Inflammation Research, Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Belgium (Y.S.).ORCID 0000-0002-0415-1506
Hisashi SawadaDepartment of Physiology, Saha Cardiovascular Research Center, Saha Aortic Center, University of Kentucky (A.D., H.S.).ORCID 0000-0003-0017-6236
Ying H ShenDivision of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery and Cardiovascular Research Institute (S.A.L., Y.L., Y.H.S.), Baylor College of Medicine, Houston, TX.ORCID 0000-0003-4119-115X
Toru SuzukiDepartment of Cardiovascular Sciences, University of Leicester and NIHR Leicester Biomedical Research Centre, United Kingdom (T.S.).ORCID 0000-0002-8371-664X
Zhen ZhouDivision of Medical Genetics, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston (D.M.M., Z.Z.).ORCID 0000-0002-7880-5998
Leducq Network on Cellular and Molecular Drivers of Acute Aortic Dissections
Funding
Genetic Predisposition To Thoracic Aortic Aneurysms/DissectionsR01HL109942 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILEWICZ, DIANNA M · 2012 to 2023
$7.5M
Determinants of Aorta HeterogeneityR35HL155649 · NHLBI · UNIVERSITY OF KENTUCKY · PI Alan Daugherty · 2021 to 2026
$5.3M
Multimodality imaging-driven multifidelity modeling of aortic dissectionU01HL142518 · NHLBI · YALE UNIVERSITY · PI HUMPHREY, JAY D., KARNIADAKIS, GEORGE · 2018 to 2022
$2.8M
Endothelial Dysfunction in the Development of Aortic Degeneration, Dissection, and RuptureR01HL159988 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI GHAGHADA, KETAN B, LEMAIRE, SCOTT A · 2022 to 2025
$2.6M
Pro-inflammatory Pyroptotic Cell Death in Aortic DegenerationR01HL158157 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI LEMAIRE, SCOTT A, SHEN, YING H · 2021 to 2024
$2.4M
ELUCIDATING MECHANISMS OF THORACIC AORTOPATHY VIA COMPUTATIONAL MODELINGR01HL169147 · NHLBI · YALE UNIVERSITY · PI Jay D. Humphrey, George Tellides · 2024 to 2026
$2.0M
Modeling Multiscale Immuno-Mechanics in Aortic DiseaseR01HL155105 · NHLBI · YALE UNIVERSITY · PI HUMPHREY, JAY D., TELLIDES, GEORGE · 2022 to 2025
There is a recent dramatic increase in research on thoracic aortic diseases that includes aneurysms, dissections, and rupture. Experimental studies predominantly use mice in which aortopathy is induced by chemical interventions, genetic manipulations, or both. Many parameters should be deliberated in experimental design in concert with multiple considerations when providing dimensional data and characterization of aortic tissues. The purpose of this review is to provide recommendations on guidance in (1) the selection of a mouse model and experimental conditions for the study, (2) parameters for standardizing detection and measurements of aortic diseases, (3) meaningful interpretation of characteristics of diseased aortic tissue, and (4) reporting standards that include rigor and transparency.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Recommendations for Design, Execution, and Reporting of Studies on Experimental Thoracic Aortopathy in Preclinical Models. · full record | Socratic