Evidence map›Paper›PMID 40079186›Full record

ReviewFASEB journal : official publication of the Federation of American Societies for Experimental Biology2025

Potential biological roles of exosomal non-coding RNAs in breast cancer.

Xiang Li, Junyi Gong, Xiang Ni, Junli Yin, Yi Zhang, Zheng Lv

Abstract readReview
In one paragraph

Review in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Potential biological roles of exosomal non-coding RNAs in breast cancer.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiang LiCancer Center, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0009-0000-4927-3876
Junyi GongCancer Center, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
Xiang NiCancer Center, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
Junli YinCancer Center, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
Yi ZhangCancer Center, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
Zheng LvCancer Center, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0009-0007-8546-5681

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) is one of the most common malignant tumors among women, accounting for 24.5% of all cancer cases and leading to 15.5% of cancer-related mortality. The treatment of BC patients remains a significant challenge due to the disease's high invasiveness, elevated metastatic potential, substantial drug resistance, and high recurrence rate. Exosomes, which are lipid-bilayer extracellular vesicles ranging in size from 30 to 150 nm, mediate intercellular communication between tumor cells and surrounding cells in the tumor microenvironment by transferring various bioactive substances, such as proteins, lipids, and nucleic acids. Recently, growing evidence has demonstrated that non-coding RNAs (ncRNAs) are enriched in exosomes and play a critical role in regulating cell proliferation, metastasis, drug resistance, and angiogenesis in BC. Consequently, exosomal ncRNAs have emerged as a promising therapeutic target for BC treatment, given their involvement in multiple processes of cancer progression. This review provides a comprehensive and in-depth analysis of emerging exosomal ncRNAs in BC, highlighting their potential biological mechanisms and advanced applications in BC treatment.

Indexed as

Breast NeoplasmsExosomesRNA, UntranslatedAnimalsFemaleGene Expression Regulation, NeoplasticHumansRNA, Long NoncodingTumor MicroenvironmentRNA, Long NoncodingRNA, Untranslatedbreast cancerexosomal ncRNAsexosomesnon‐coding RNAs

Identifiers

PMID40079186
PMCPMC11904755

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.