Evidence map›Paper›PMID 40079311›Full record

Observational studyJournal of the American Heart Association2025

Cerebral Hemodynamic Impairment and Cognitive Dysfunction in

Yoshinori Kakino, Yorito Hattori, Soshiro Ogata, Yuriko Nakaoku, Kunihiro Nishimura, Hidehiro Iida, Masafumi Ihara

Abstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yoshinori KakinoDepartment of Neurology National Cerebral and Cardiovascular Center Suita, Osaka Japan.
Yorito HattoriDepartment of Neurology National Cerebral and Cardiovascular Center Suita, Osaka Japan.ORCID 0000-0002-1495-4433
Soshiro OgataDepartment of Preventive Medicine and Epidemiology National Cerebral and Cardiovascular Center Suita, Osaka Japan.ORCID 0000-0002-0100-376X
Yuriko NakaokuDepartment of Preventive Medicine and Epidemiology National Cerebral and Cardiovascular Center Suita, Osaka Japan.ORCID 0000-0002-3100-574X
Kunihiro NishimuraDepartment of Preventive Medicine and Epidemiology National Cerebral and Cardiovascular Center Suita, Osaka Japan.ORCID 0000-0002-0639-0949
Hidehiro IidaTurku PET Centre University of Turku and Turku General Hospital Turku Finland.ORCID 0000-0002-7914-3068
Masafumi IharaDepartment of Neurology National Cerebral and Cardiovascular Center Suita, Osaka Japan.ORCID 0000-0002-7102-4048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur previous preclinical study demonstrated that METHODS AND

resultsA cross-sectional observational study was conducted between January 2017 and March 2022. In a primary analysis, 91 subjects (114 affected cerebral hemispheres) with asymptomatic carotid artery stenosis or occlusion who underwent neuropsychological examinations and

conclusions

Indexed as

Apolipoprotein E4Carotid StenosisCerebrovascular CirculationCognitionCognitive DysfunctionHemodynamicsAgedAsymptomatic DiseasesCross-Sectional StudiesFemaleHeterozygoteHumansMaleMiddle AgedPositron-Emission TomographyRisk FactorsApolipoprotein E4APOE4carotid artery occlusioncarotid artery stenosiscerebral blood flowmemory

Identifiers

PMID40079311
PMCPMC12132685

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.