Evidence map›Paper›PMID 40079563›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2025

Characterizing the protective vasodilatory effects of hypobaric hypoxia on the neurovascular coupling response.

Jack K Leacy, David P Burns, Nicholas G Jendzjowsky, Connor Braun, Brittney A Herrington, Richard Ja Wilson, Tyler D Vermeulen, Glen E Foster, Alexander J Rosenberg, Garen K Anderson and 4 more

Abstract read
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In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jack K LeacyDepartment of Physiology, School of Medicine, College of Medicine and Health, University College Cork, Cork, Ireland.
David P BurnsDepartment of Physiology, School of Medicine, College of Medicine and Health, University College Cork, Cork, Ireland.
Nicholas G JendzjowskyHotchkiss Brain institute, University of Calgary, Calgary, Alberta, Canada.
Connor BraunHotchkiss Brain institute, University of Calgary, Calgary, Alberta, Canada.
Brittney A HerringtonHotchkiss Brain institute, University of Calgary, Calgary, Alberta, Canada.
Richard Ja WilsonHotchkiss Brain institute, University of Calgary, Calgary, Alberta, Canada.
Tyler D VermeulenSchool of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, British Columbia, USA.
Glen E FosterSchool of Health and Exercise Sciences, Faculty of Health and Social Development, University of British Columbia Okanagan, British Columbia, USA.
Alexander J RosenbergCerebral and Cardiovascular Physiology Laboratory, School of Biomedical Sciences, University of North Texas Health Science Centre, Texas, USA.ORCID 0000-0002-0133-1288
Garen K AndersonCerebral and Cardiovascular Physiology Laboratory, School of Biomedical Sciences, University of North Texas Health Science Centre, Texas, USA.
Caroline A RickardsCerebral and Cardiovascular Physiology Laboratory, School of Biomedical Sciences, University of North Texas Health Science Centre, Texas, USA.
Eric F LuckingDepartment of Physiology, School of Medicine, College of Medicine and Health, University College Cork, Cork, Ireland.
Ken D O'HalloranDepartment of Physiology, School of Medicine, College of Medicine and Health, University College Cork, Cork, Ireland.
Trevor A DayDepartment of Physiology, School of Medicine, College of Medicine and Health, University College Cork, Cork, Ireland.ORCID 0000-0001-7102-4235

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurovascular coupling (NVC) is the link between local neuronal activity and regional cerebral blood flow. High altitude (HA) ascent induces acute hypoxic vasodilation of the cerebral vasculature, with associated changes in CO

Indexed as

Cerebrovascular CirculationHypoxiaNeurovascular CouplingVasodilationAdultAltitudeAltitude SicknessBlood Flow VelocityFemaleHumansMaleUltrasonography, Doppler, TranscranialYoung AdultacclimatizationCerebral blood flowhigh altitudehypobaric hypoxianeurovascular couplingtranscranial Doppler ultrasound

Identifiers

PMID40079563
PMCPMC11907632

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.