Evidence map›Paper›PMID 40080351›Full record

ArticleCell biochemistry and biophysics2025

Determination of the Inhibitory Potential of Chalcones on Myeloperoxidase Enzyme Activity: In vitro and Molecular Docking Studies.

Nurgül Abul, Yeliz Demir, Aykut Öztekin, Hasan Özdemir

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Article in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Exploring the Role of Phytoconstituent FromFood science & nutrition · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nurgül AbulAtaturk University, Faculty of Science, Department of Chemistry, Erzurum, Türkiye.
Yeliz DemirAtaturk University, Faculty of Science, Department of Chemistry, Erzurum, Türkiye. yelizdemir@ardahan.edu.tr.
Aykut ÖztekinAgri Ibrahim Cecen University, Health Services of Vocational School, Agri, Türkiye.
Hasan ÖzdemirAtaturk University, Faculty of Science, Department of Chemistry, Erzurum, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myeloperoxidase (MPO) is a highly abundant hemoprotein in neutrophils and monocytes. It has a crucial function in immunological surveillance and the body's defensive systems. Nevertheless, there is a strong correlation between elevated MPO activity and the development and advancement of inflammatory processes. Chalcone derivatives serve as fundamental components of pharmaceutical raw materials, which have been extensively utilized for the treatment of several ailments. In this study, it was studied the effect of some chalchones on MPO activity. Chalcones (1-6) strongly inhibited MPO with IC

Indexed as

ChalconesEnzyme InhibitorsMolecular Docking SimulationPeroxidaseCatalytic DomainHumansHydrogen BondingChalconesEnzyme InhibitorsPeroxidaseChalconeEnzyme inhibitionIn silicoMyeloperoxidase

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.