Evidence map›Paper›PMID 40082385›Full record

ArticleObesity surgery2025

Efficacy of Metabolic and Bariatric Surgery for the Treatment of Recurrent Hypertriglyceridemia-Induced Acute Pancreatitis.

Zhenghang Yu, Dianyuan Liang, Zhongyang Zhang, Ke Song, Yuan Zhang, Yin Xian, Ming He, Xing Xie, Sijun Xie, Xiangxin Kong and 1 more

Abstract read
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In one paragraph

Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhenghang YuInstitute of Hepatobiliary Pancreatic Intestinal Diseases, North Sichuan Medical College, Nanchong, 637000, China.
Dianyuan LiangInstitute of Hepatobiliary Pancreatic Intestinal Diseases, North Sichuan Medical College, Nanchong, 637000, China.
Zhongyang ZhangInstitute of Hepatobiliary Pancreatic Intestinal Diseases, North Sichuan Medical College, Nanchong, 637000, China.
Ke SongInstitute of Hepatobiliary Pancreatic Intestinal Diseases, North Sichuan Medical College, Nanchong, 637000, China.
Yuan ZhangDepartment of Gastroenterology, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China.
Yin XianNanchong Psychosomatic Hospital, Nanchong, 637770, China.
Ming HeDepartment of Gastroenterology, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China.
Xing XieDepartment of Gastroenterology, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China.
Sijun XieDepartment of Gastroenterology, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China.
Xiangxin KongEngineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China. kxxxxsc@tju.edu.cn.
Yixing RenDepartment of Gastroenterology, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, China. yixingren@nsmc.edu.cn.

Funding

Health Commission of Sichuan Province 23LCYJ031National Natural Science Foundation of China 82070535Natural Science Foundation of Sichuan Province 2023JDRC0091
6 · The paper itself

Abstract

backgroundObesity is a predisposing factor for the onset of hypertriglyceridemia-induced acute pancreatitis (HTG-AP). Metabolic and bariatric surgery (MBS) has demonstrated significant short-term efficacy in the treatment of HTG-AP. The current evaluated the long-term efficacy of MBS for the management of recurrent HTG-AP.

methodsBetween 01 January 2015 and 31 August 2019, a total of 51 patients diagnosed with obesity combined with HTG-AP at our hospital were enrolled in the study. 14 underwent laparoscopic sleeve gastrectomy (LSG), 9 underwent laparoscopic Roux-en-Y gastric bypass (LRYGB), and 28 underwent routine treatment including dietary therapy, pharmacotherapy, and plasma exchange. The aim of the study was to investigate the long-term therapeutic effects of LRYGB, LSG, and routine treatment on recurrent HTG-AP, and to assess patient prognoses under different treatment modalities.

resultsThe LSG and LRYGB groups achieved significant average weight loss, whereas the changes in the routine treatment group were not significant. The LRYGB group exhibited more weight loss than the LSG group. In both the LSG and LRYGB groups triglyceride levels decreased significantly within the first year after surgery. The routine treatment group exhibited a pancreatitis recurrence rate of 57.14%, compared to 15.38% in the LSG group and 11.11% in the LRYGB group.

conclusionsOver a period of 5 years, LSG and LRYGB exhibited superior efficacy with respect to managing metabolic syndrome associated with recurrent HTG-AP, particularly by enhancing weight management and reducing the pancreatitis recurrence rate. These findings support the long-term efficacy of MBS for the treatment of recurrent HTG-AP.

Indexed as

Bariatric SurgeryGastrectomyGastric BypassHypertriglyceridemiaObesity, MorbidPancreatitisAcute DiseaseAdultFemaleHumansLaparoscopyMaleMiddle AgedRecurrenceRetrospective StudiesTreatment OutcomeAcute pancreatitisHypertriglyceridemiaLaparoscopic Roux-en-Y gastric bypassLaparoscopic sleeve gastrectomyObesity

Identifiers

PMID40082385

What Socratic holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.